One-Pot Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles in Ionic Liquid

被引:12
|
作者
Wan, Yu [2 ]
Liu, Gui-xiang [1 ]
Zhao, Ling-ling [1 ]
Wang, Hai-ying [1 ]
Huang, Shu-ying [1 ]
Chen, Liang-feng [1 ]
Wu, Hui [1 ,2 ]
机构
[1] Jiangsu Normal Univ, Jiangsu Key Lab Green Synth Funct Mat, Sch Chem & Chem Engn, Xuzhou 221116, Peoples R China
[2] Jiangsu Key Lab Biotechnol Med Plant, Xuzhou 221116, Peoples R China
关键词
SOLVENT-FREE SYNTHESIS; TETRASUBSTITUTED IMIDAZOLES; EFFICIENT;
D O I
10.1002/jhet.1751
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The four-component condensation of benzil, aromatic aldehyde, primary amine, and ammonium acetate catalyzed by TFA in ionic liquid [Bpy]BF4 at 80 degrees C provided 1,2,4,5-tetrasubstituted imidazoles in moderate to high yields.
引用
收藏
页码:713 / 718
页数:6
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