Reactivity of some pyrazole-3-carboxylic acid derivatives towards Grignard reagent

被引：0

作者：

Korkusuz, Elif ^{[1
]}

Yildirim, Ismail ^{[2
]}

机构：

[1] Erciyes Univ, Kayseri Vocat Coll, TR-38039 Kayseri, Turkey

[2] Erciyes Univ, Fac Sci, Dept Chem, TR-38039 Kayseri, Turkey

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2017年 / 56卷 / 02期

关键词：

Furan-2,3-dione; pyrazole-3-carboxylic acid; Grignard reagent; furo[3,4-c]pyrazol-6-one; substituted-1H-pyrazole; methylmagnesium chloride; CYCLIC OXALYL COMPOUNDS; 4-BENZOYL-1,5-DIPHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID; CHLORIDE; FUNCTIONALIZATION; MECHANISM;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 1H-pyrazole-3-carboxylic acid derivatives with methylmagnesium chloride results in the formation of 1-aryl-5-phenyl-4-(1-phenyletheny1)-1H-pyrazoles 5,7, furo-pyrazolones 6, 4-substituted-3-(1-hyaroxy-l-methylethyl) -1,5-diaryl-1H-pyrazoles 8,9 and 3-acy1-4-(1-hydroxy-1-phenylethyl)-1-ary1-5-pheny1-1H-pyrazoles 11,13. The structures of all new synthesized compounds have been established by H-1, and C-13 NMR, as well as 2D COSY, FT-IR. spectroscopic data, and elemental analyses.

引用

页码：152 / 159

页数：8

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