SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NOVEL BENZOFURAN ESTER DERIVATIVES

被引：0

作者：

Vakharia, Jyot ^{[1
]}

Gangan, Vijay D. ^{[2
]}

Chakraborty, Chaitaly T. ^{[2
]}

Bhawe, Vijay G. ^{[1
]}

Bhalekar, Satish M. ^{[3
]}

机构：

[1] Bhavans Coll Arts Sci & Commerce, Dept Chem, Bombay 400058, Maharashtra, India

[2] Thakur Coll Sci & Commerce, Dept Chem, Bombay 400101, Maharashtra, India

[3] SIWS Coll, Dept Chem, Bombay 400031, Maharashtra, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 23卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl (E)-3-[2-(4-hydroxy-3-methoxy phenyl)-7-methoxy-3-methoxycarbonyl-2,3dihydro-1-benzofuran-5-yl] prop-2-enoate constitute a new group of antimitotic and potential anticancer agents that inhibit tubulin polymerization. It is a benzofuranoid type neolignan that have been synthesized and diversified to its respective ester (Pyridine/DCM/Acetyl/Benzoyl chloride) derivatives using conventional method and characterized by H-1 NMR, IR, elemental analysis and mass spectral data. These synthesized compounds were screened for their antibacterial activity against Gram positive and Gram negative cultures. Few of them possess promising antibacterial activity.

引用

页码：315 / 320

页数：6

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