Coenzyme Q changes in liver and plasma in the rat after partial hepatectomy

被引：0
|
作者：
Castelluccio, C [1 ]
Formiggini, G [1 ]
Pich, MM [1 ]
Geneva, ML [1 ]
Bovina, C [1 ]
Marchetti, M [1 ]
Lenaz, G [1 ]
机构：
[1] UNIV BOLOGNA,DEPT BIOCHEM G MORUZZI,I-40126 BOLOGNA,ITALY
来源：
MOLECULAR ASPECTS OF MEDICINE | 1997年 / 18卷
关键词：
coenzyme Q; liver regeneration; plasma; mitochondria; antioxidant;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The levels of coenzyme Q were determined in brood plasma and regenerating liver mitochondria of hepatectomized rats, using as controls either sham-operated or non-operated animals. Mitochondrial CoQ(9) content increased in sham-operated rats, whereas it was significantly lower in hepatectomized with respect to non-operated animals. Plasma CoQ(9) levels decreased dramatically in hepatectomized animals, but increased strongly in sham-operated in comparison with non-operated rats. The data suggest the possibility of a rate-limiting step in CoQ biosynthesis in hepatectomized animals.
引用
收藏
页码：S275 / S278
页数：4
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