Coenzyme Q changes in liver and plasma in the rat after partial hepatectomy

被引：0

作者：

Castelluccio, C ^{[1
]}

Formiggini, G ^{[1
]}

Pich, MM ^{[1
]}

Geneva, ML ^{[1
]}

Bovina, C ^{[1
]}

Marchetti, M ^{[1
]}

Lenaz, G ^{[1
]}

机构：

[1] UNIV BOLOGNA,DEPT BIOCHEM G MORUZZI,I-40126 BOLOGNA,ITALY

来源：

MOLECULAR ASPECTS OF MEDICINE | 1997年 / 18卷

关键词：

coenzyme Q; liver regeneration; plasma; mitochondria; antioxidant;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The levels of coenzyme Q were determined in brood plasma and regenerating liver mitochondria of hepatectomized rats, using as controls either sham-operated or non-operated animals. Mitochondrial CoQ(9) content increased in sham-operated rats, whereas it was significantly lower in hepatectomized with respect to non-operated animals. Plasma CoQ(9) levels decreased dramatically in hepatectomized animals, but increased strongly in sham-operated in comparison with non-operated rats. The data suggest the possibility of a rate-limiting step in CoQ biosynthesis in hepatectomized animals.

引用

页码：S275 / S278

页数：4

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