Modulation of Aquaporins by Dietary Patterns and Plant Bioactive Compounds

被引：8

作者：

Cataldo, Ilaria ^{[1
]}

Maggio, Anna ^{[1
]}

Gena, Patrizia ^{[1
]}

de Bari, Ornella ^{[2
]}

Tamma, Grazia ^{[1
]}

Portincasa, Piero ^{[2
]}

Calamita, Giuseppe ^{[1
]}

机构：

[1] Univ Bari Aldo Moro, Med Sch, Dept Biosci Biotechnol & Biopharmaceut, Bari, Italy

[2] Univ Bari Aldo Moro, Med Sch, Dept Biomed Sci & Human Oncol, Clin Med A Murri, Bari, Italy

来源：

CURRENT MEDICINAL CHEMISTRY | 2019年 / 26卷 / 19期

基金：

美国国家卫生研究院;

关键词：

Nutraceuticals; polyphenols; functional food; metabolic syndrome; gut microbiota; aquaporins; FATTY LIVER-DISEASE; SPINAL-CORD-INJURY; INSULIN-RESISTANCE; MOLECULAR CHARACTERIZATION; APPLE POLYPHENOL; UREA TRANSPORTER; OXIDATIVE STRESS; GENE-EXPRESSION; DOWN-REGULATION; WATER CHANNELS;

D O I：

10.2174/0929867324666170523123010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Healthful dietary patterns and bioactive compounds supplementation can be adopted as simple and easy intervention to prevent, attenuate or cure clinical disorders, especially when it comes to degenerative and chronic diseases. In the recent years, a growing body of evidence indicates Aquaporins (AQPs), a family of membrane channel proteins widely expressed in the human body, among the targets underlying the beneficial action played by some food nutrients and phytochemical compounds. Here, we provide an overview of what is known regarding the AQP modulation exerted by healthful dietary patterns and plant polyphenols.

引用

页码：3457 / 3470

页数：14

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