stem cell transplantation;
umbilical cord blood;
alternative stem cell sources;
BONE-MARROW-TRANSPLANTATION;
ACUTE LYMPHOBLASTIC-LEUKEMIA;
FANCONI-ANEMIA PATIENTS;
LYMPHOMA WORKING PARTY;
ACUTE MYELOID-LEUKEMIA;
RISK-FACTOR ANALYSIS;
UNRELATED DONORS;
PEDIATRIC-PATIENTS;
EUROPEAN GROUP;
NONMALIGNANT DISEASES;
D O I:
10.1111/j.1365-2141.2009.07828.x
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
P>Umbilical cord blood has rapidly become a valuable alternative stem cell source for allogeneic haematopoietic stem cell transplantation. Extensive research over the last 20 years has established the safety and efficacy of umbilical cord blood transplantation in both children and adults with a variety of malignant and non-malignant diseases. This research has clearly shown that this stem cell source has several unique characteristics resulting in distinct advantages and disadvantages when compared to transplantation with unrelated bone marrow or peripheral blood stem cells. This article reviews the most recent literature comparing the outcomes after umbilical cord blood transplantation with other alternative stem cell sources.
机构:
Fate Therapeut, San Diego, CA USADana Farber Canc Inst, Boston, MA 02215 USA
Multani, Pratik
Robbins, David
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h-index: 0
机构:
Fate Therapeut, San Diego, CA USADana Farber Canc Inst, Boston, MA 02215 USA
Robbins, David
Kim, Haesook T.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Kim, Haesook T.
Thuy Le
论文数: 0引用数: 0
h-index: 0
机构:
Fate Therapeut, San Diego, CA USADana Farber Canc Inst, Boston, MA 02215 USA
Thuy Le
Hoggatt, Jonathan
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Stem Cell Inst, Cambridge, MA USA
Massachusetts Gen Hosp, Boston, MA 02114 USADana Farber Canc Inst, Boston, MA 02215 USA
Hoggatt, Jonathan
Pelus, Louis M.
论文数: 0引用数: 0
h-index: 0
机构:
Indiana Univ, Indianapolis, IN 46204 USADana Farber Canc Inst, Boston, MA 02215 USA
Pelus, Louis M.
Desponts, Caroline
论文数: 0引用数: 0
h-index: 0
机构:
Fate Therapeut, San Diego, CA USADana Farber Canc Inst, Boston, MA 02215 USA
Desponts, Caroline
Chen, Yi-Bin
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Boston, MA 02114 USADana Farber Canc Inst, Boston, MA 02215 USA
Chen, Yi-Bin
Rezner, Betsy
论文数: 0引用数: 0
h-index: 0
机构:
Fate Therapeut, San Diego, CA USADana Farber Canc Inst, Boston, MA 02215 USA
Rezner, Betsy
Armand, Philippe
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Armand, Philippe
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Koreth, John
Glotzbecker, Brett
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Glotzbecker, Brett
Ho, Vincent T.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Ho, Vincent T.
Alyea, Edwin
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Alyea, Edwin
Isom, Marlisa
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Isom, Marlisa
Kao, Grace
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Kao, Grace
Armant, Myriam
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp, Boston, MA 02115 USADana Farber Canc Inst, Boston, MA 02215 USA
Armant, Myriam
Silberstein, Leslie
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Stem Cell Inst, Cambridge, MA USA
Childrens Hosp, Boston, MA 02115 USADana Farber Canc Inst, Boston, MA 02215 USA
Silberstein, Leslie
Hu, Peirong
论文数: 0引用数: 0
h-index: 0
机构:
Indiana Univ, Indianapolis, IN 46204 USADana Farber Canc Inst, Boston, MA 02215 USA
Hu, Peirong
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机构:
Soiffer, Robert J.
Scadden, David T.
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Stem Cell Inst, Cambridge, MA USA
Massachusetts Gen Hosp, Boston, MA 02114 USADana Farber Canc Inst, Boston, MA 02215 USA
Scadden, David T.
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Ritz, Jerome
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Goessling, Wolfram
North, Trista E.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USA
Harvard Stem Cell Inst, Cambridge, MA USA
Beth Israel Deaconess Med Ctr, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
North, Trista E.
Mendlein, John
论文数: 0引用数: 0
h-index: 0
机构:
Fate Therapeut, San Diego, CA USADana Farber Canc Inst, Boston, MA 02215 USA
Mendlein, John
Ballen, Karen
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Boston, MA 02114 USADana Farber Canc Inst, Boston, MA 02215 USA
Ballen, Karen
Zon, Leonard I.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USA
Harvard Stem Cell Inst, Cambridge, MA USA
Childrens Hosp, Boston, MA 02115 USA
Howard Hughes Med Inst, Chevy Chase, MD USADana Farber Canc Inst, Boston, MA 02215 USA
Zon, Leonard I.
Antin, Joseph H.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02215 USADana Farber Canc Inst, Boston, MA 02215 USA
Antin, Joseph H.
Shoemaker, Daniel D.
论文数: 0引用数: 0
h-index: 0
机构:
Fate Therapeut, San Diego, CA USADana Farber Canc Inst, Boston, MA 02215 USA
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Jacobson, Caron A.
Turki, Amin T.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Turki, Amin T.
McDonough, Sean M.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
McDonough, Sean M.
Steyenson, Kristen E.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Steyenson, Kristen E.
Kim, Haesook T.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Kim, Haesook T.
Kao, Grace
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Connell OReilly Cell Manipulat Core Facil, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Kao, Grace
Herrera, Maria I.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Herrera, Maria I.
Reynolds, Carol G.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Reynolds, Carol G.
Alyea, Edwin P.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Alyea, Edwin P.
Ho, Vincent T.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Ho, Vincent T.
论文数: 引用数:
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机构:
Koreth, John
Armand, Philippe
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Armand, Philippe
Chen, Yi-Bin
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Massachusetts Gen Hosp, Sch Med, Div Hematol Oncol, Boston, MA USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Chen, Yi-Bin
Ballen, Karen
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Massachusetts Gen Hosp, Sch Med, Div Hematol Oncol, Boston, MA USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Ballen, Karen
论文数: 引用数:
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机构:
Soiffer, Robert J.
Antin, Joseph H.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
Antin, Joseph H.
Cutler, Corey S.
论文数: 0引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USADana Farber Canc Inst, Div Hematol Malignancies, Boston, MA 02215 USA
机构:
Inst Super Tecn, Dept Bioengn, Lisbon, Portugal
Inst Super Tecn, Inst Biotechnol & Bioengn, Lisbon, Portugal
Cell2b, Adv Therapeut, Cantanhede, PortugalInst Super Tecn, Dept Bioengn, Lisbon, Portugal
Andrade, Pedro Z.
dos Santos, Francisco
论文数: 0引用数: 0
h-index: 0
机构:
Inst Super Tecn, Dept Bioengn, Lisbon, Portugal
Inst Super Tecn, Inst Biotechnol & Bioengn, Lisbon, Portugal
Cell2b, Adv Therapeut, Cantanhede, PortugalInst Super Tecn, Dept Bioengn, Lisbon, Portugal
dos Santos, Francisco
Cabral, Joaquim M. S.
论文数: 0引用数: 0
h-index: 0
机构:
Inst Super Tecn, Dept Bioengn, Lisbon, Portugal
Inst Super Tecn, Inst Biotechnol & Bioengn, Lisbon, PortugalInst Super Tecn, Dept Bioengn, Lisbon, Portugal
Cabral, Joaquim M. S.
da Silva, Claudia L.
论文数: 0引用数: 0
h-index: 0
机构:
Inst Super Tecn, Dept Bioengn, Lisbon, Portugal
Inst Super Tecn, Inst Biotechnol & Bioengn, Lisbon, PortugalInst Super Tecn, Dept Bioengn, Lisbon, Portugal