Neutrophils in traumatic brain injury (TBI): friend or foe?

被引：107

作者：

Liu, Yang-Wuyue ^{[1
,2
]}

Li, Song ^{[2
]}

Dai, Shuang-Shuang ^{[1
,3
]}

机构：

[1] Army Med Univ, Dept Biochem & Mol Biol, Chongqing 400038, Peoples R China

[2] Univ Pittsburgh, Sch Pharm, Ctr Pharmacogenet, Pittsburgh, PA 15261 USA

[3] Army Med Univ, Daping Hosp, State Key Lab Trauma Burn & Combined Injury, Mol Biol Ctr, Chongqing 400042, Peoples R China

来源：

JOURNAL OF NEUROINFLAMMATION | 2018年 / 15卷

基金：

中国国家自然科学基金;

关键词：

Neutrophils; Polymorphonuclear cell; Traumatic brain injury; Edema; Neuroinflammation; Blood-brain barrier; Neurodegeneration; Nerve recovery; CEREBRAL-ARTERY OCCLUSION; COLONY-STIMULATING FACTOR; ENDOTHELIAL GROWTH-FACTOR; ACTIVATED PROTEIN-KINASE; ISCHEMIC CELL-DAMAGE; SPINAL-CORD-INJURY; CEREBROSPINAL-FLUID; OXIDATIVE STRESS; IN-VITRO; BLOOD-FLOW;

D O I：

10.1186/s12974-018-1173-x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited. Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated immune cells at the sites of injury, are highly involved in the initiation, development, and recovery of TBI. Nonetheless, our understanding about neutrophils in TBI is obsolete, and mounting evidences from recent studies have challenged the conventional views. This review summarizes what is known about the relationships between neutrophils and pathophysiology of TBI. In addition, discussions are made on the complex roles as well as the controversial views of neutrophils in TBI.

引用

页数：18

共 50 条

[31] PITUITARY DYSFUNCTION AFTER TRAUMATIC BRAIN INJURY (TBI)
Lohawala, A.
El-Nimr, G.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2011, 82 (08):
[32] Mild Traumatic Brain Injury (TBI): What Is the Complication?
Choe, Meeryo
Zeiger, Max
Yudovin, Sue
McArthur, David
Giza, Christopher
NEUROLOGY, 2016, 86
[33] Hypopituitarism post traumatic brain injury (TBI): review
Kgosidialwa, Oratile
Agha, Amar
IRISH JOURNAL OF MEDICAL SCIENCE, 2019, 188 (04) : 1201 - 1206
[34] Traumatic brain injury (TBI) in older adults: aging with a TBI versus incident TBI in the aged
Peters, Matthew E.
INTERNATIONAL PSYCHOGERIATRICS, 2016, 28 (12) : 1931 - 1934
[35] Neutrophils: Friend, foe, or contextual ally in myocardial healing
Halade, Ganesh V.
Ma, Yonggang
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2016, 97 : 44 - 46
[36] Neurobehavioural deficits after severe traumatic brain injury (TBI)
Lippert-Gruener, Marcella
Kuchta, Johannes
Hellmich, Martin
Klug, Norfrid
BRAIN INJURY, 2006, 20 (06) : 569 - 574
[37] Broken lives - Rehabilitation of people with traumatic brain injury (TBI)
Nazarowa, L. J. Helwig
Hoogma, R.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2012, 56 (7-8) : 809 - 809
[38] Cavitation as a Possible Traumatic Brain Injury (TBI) Damage Mechanism
Wardlaw, Andrew
Goeller, Jack
26TH SOUTHERN BIOMEDICAL ENGINEERING CONFERENCE: SBEC 2010, 2010, 32 : 34 - 37
[39] Alteration of the Circadian Network after Traumatic Brain Injury (TBI)
Saeman, Melody R.
Gatson, Joshua W.
Liu, Ming-Mei
Wolf, Steven E.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2014, 219 (03) : S68 - S68
[40] EVALUATION OF FIBRINOGENIC FUNCTION IN ACUTE TRAUMATIC BRAIN INJURY (TBI)
Bardon, J.
Gaide-Chevronnay, L.
Bouzat, P.
Declety, P.
Picard, J.
Marlu, R.
Francony, G.
Brun, J.
Quesada, J. L.
Jacquot, C.
Albaladejo, P.
Payen, J. F.
INTENSIVE CARE MEDICINE, 2011, 37 : S48 - S48

← 1 2 3 4 5 →