Synthesis of Novel Tricyclic 1,5-Benzothiazepine Derivatives Bearing Quinoline Moiety via [2+2] Cycloaddition Reaction

被引：2

作者：

Huang, Le ^{[1
]}

Liu, Fang-Ming ^{[1
]}

Dong, Zhi-Qiang ^{[1
]}

机构：

[1] Hangzhou Normal Univ, Coll Mat Chem & Chem Engn, Hangzhou 310036, Zhejiang, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 51卷 / 05期

关键词：

BETA-LACTAMS; 1,3-DIPOLAR CYCLOADDITION; CRYSTAL-STRUCTURE; INHIBITORS; DESIGN; ALKALOIDS;

D O I：

10.1002/jhet.1808

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of new tricyclic 1,5-benzothiazepine derivatives were synthesized by the reaction of 1,5-benzothiazepine containing 2-phenoxy-quinoline with chloracetyl chloride and phenoxyacetyl chloride. The structures of the target compounds were confirmed by IR, H-1 NMR MS, and elemental analysis.

引用

页码：1516 / 1521

页数：6

共 50 条

[41] Microwave promoted a green protocol for solvent free synthesis of 1,5-benzothiazepine and [1,3,4]-thiadiazepine derivatives incorporating thiophene moiety
Saleh, Tamer S.
Abd El-Rahman, Naglaa M.
Assaker, Ramy S. A.
GREEN CHEMISTRY LETTERS AND REVIEWS, 2012, 5 (03) : 315 - 320
[42] Synthesis of Novel 1,3-Cyclohexadiene Derivatives Bearing 2-Oxo-Quinoline Moiety via a 4-CR Strategy**
Rezvanian, Atieh
Kuhzadeh, Parisa
Roosta, Atefeh
CHEMISTRYSELECT, 2021, 6 (45): : 12965 - 12969
[43] An Unexpected Synthesis of Novel Oxygen-Bridged 1,5-Benzothiazepine Derivatives and their Reductive Five-Membered-Ring Opening
Roshan Ahmad
Mohammad Zia-ul-Haq
Shahid Hameed
Humaira Akhtar
Helmut Duddeck
Monatshefte für Chemie / Chemical Monthly, 2000, 131 : 393 - 400
[44] Intramolecular [2+2]-Cycloaddition in the Synthesis of Polycyclic Tetrahydrothiopyran Derivatives Bearing a Cyclobutane Scaffold
Grzelak, Paulina
Saktura, Maciej
Sieron, Leslaw
Albrecht, Lukasz
ADVANCED SYNTHESIS & CATALYSIS, 2019, 361 (10) : 2274 - 2279
[45] Synthesis and Crystal Structure of a β-Lactam Derivative of 2,4-Diaryl-1,5-Benzothiazepine
LI Yuan a* DU Cai Yun b YANG Qiu Qing a (a. Department of Chemistry
结构化学, 1999, (01) : 59 - 62
[46] Synthesis and crystal structure of a β-lactam derivative of 2,4-diaryl-1,5-benzothiazepine
Li, Y
Du, CY
Yang, QQ
Jin, S
Xing, QY
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 1999, 18 (01) : 57 - 60
[47] An unexpected synthesis of novel oxygen-bridged 1,5-benzothiazepine derivatives and their reductive five-membered-ring opening
Ahmad, R
Zia-ul-Haq, M
Hameed, S
Akhtar, H
Duddeck, H
MONATSHEFTE FUR CHEMIE, 2000, 131 (04): : 393 - 400
[48] NOVEL AND FACILE ROUTE TO (+/-)-PHYSOVENINE VIA INTRAMOLECULAR [2+2]CYCLOADDITION REACTION
SHISHIDO, K
AZUMA, T
SHIBUYA, M
TETRAHEDRON LETTERS, 1990, 31 (02) : 219 - 220
[49] Derivatives of 4-(2-hydroxylphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine
Parvez, M
Umbreen, S
Ansari, FL
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2003, 59 : O298 - O301
[50] SYNTHESIS, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF SOME NEW DERIVATIVES OF BENZOTHIAZOLE, 1,4-BENZOTHIAZINE AND 1,5-BENZOTHIAZEPINE
GRANDOLINI, G
AMBROGI, V
ROSSI, C
TIRALTI, MC
TUTTOBELLO, L
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1986, 21 (06) : 455 - 460

← 1 2 3 4 5 →