Synthesis of Novel Tricyclic 1,5-Benzothiazepine Derivatives Bearing Quinoline Moiety via [2+2] Cycloaddition Reaction

被引：2

作者：

Huang, Le ^{[1
]}

Liu, Fang-Ming ^{[1
]}

Dong, Zhi-Qiang ^{[1
]}

机构：

[1] Hangzhou Normal Univ, Coll Mat Chem & Chem Engn, Hangzhou 310036, Zhejiang, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2014年 / 51卷 / 05期

关键词：

BETA-LACTAMS; 1,3-DIPOLAR CYCLOADDITION; CRYSTAL-STRUCTURE; INHIBITORS; DESIGN; ALKALOIDS;

D O I：

10.1002/jhet.1808

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of new tricyclic 1,5-benzothiazepine derivatives were synthesized by the reaction of 1,5-benzothiazepine containing 2-phenoxy-quinoline with chloracetyl chloride and phenoxyacetyl chloride. The structures of the target compounds were confirmed by IR, H-1 NMR MS, and elemental analysis.

引用

页码：1516 / 1521

页数：6

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