Single-cell analysis of autoreactive B cells in patients with systemic sclerosis revealed that responses to therapy are determined by effector and regulatory B cell balance

被引:0
|
作者
Ebata, Satoshi [1 ]
Yoshizaki, Ayumi [1 ]
Fukasawa, Takemichi [1 ]
Sato, Shinichi [1 ]
机构
[1] Univ Tokyo, Tokyo, Japan
来源
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
16
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Cytokine-producing B-cell balance associates with skin fibrosis in patients with systemic sclerosis
    Horii, Motoki
    Fushida, Natsumi
    Ikeda, Tomoyuki
    Oishi, Kyosuke
    Hamaguchi, Yasuhito
    Ikawa, Yuichi
    Komuro, Akito
    Matsushita, Takashi
    JOURNAL OF DERMATOLOGY, 2022, 49 (10): : 1012 - 1019
  • [42] B-cell–Targeted Therapy for the Fibrotic Complications of Systemic Sclerosis
    Robert Woodrick
    John Varga
    Current Rheumatology Reports, 2011, 13 : 1 - 3
  • [43] B-cell-Targeted Therapy for the Fibrotic Complications of Systemic Sclerosis
    Woodrick, Robert
    Varga, John
    CURRENT RHEUMATOLOGY REPORTS, 2011, 13 (01) : 1 - 3
  • [44] Lymph Node Stromal Cells Generate Antigen-Specific Regulatory T Cells and Control Autoreactive T and B Cell Responses
    Nadafi, Reza
    de Graca, Catarina Gago
    Keuning, Eelco D.
    Koning, Jasper J.
    de Kivit, Sander
    Konijn, Tanja
    Henri, Sandrine
    Borst, Jannie
    Reijmers, Rogier M.
    van Baarsen, Lisa G. M.
    Mebius, Reina E.
    CELL REPORTS, 2020, 30 (12): : 4110 - +
  • [45] Restoration of regulatory B cell deficiency following alemtuzumab therapy in patients with relapsing multiple sclerosis
    Kim, Yeseul
    Kim, Gayoung
    Shin, Hyun-June
    Hyun, Jae-Won
    Kim, Su-Hyun
    Lee, Eunjig
    Kim, Ho Jin
    JOURNAL OF NEUROINFLAMMATION, 2018, 15
  • [46] Restoration of regulatory B cell deficiency following alemtuzumab therapy in patients with relapsing multiple sclerosis
    Yeseul Kim
    Gayoung Kim
    Hyun-June Shin
    Jae-Won Hyun
    Su-Hyun Kim
    Eunjig Lee
    Ho Jin Kim
    Journal of Neuroinflammation, 15
  • [47] Restoration of Regulatory B Cell Deficiency Following Alemtuzumab Therapy in Patients with Active Multiple Sclerosis
    Kim, Yeseul
    Kim, Gayoung
    Shin, Hyun-June
    Hyun, Jae-Won
    Kim, Su-Hyun
    Kim, Ho Jin
    MULTIPLE SCLEROSIS JOURNAL, 2018, 24 (03) : 401 - 401
  • [48] Single-Cell RNA Sequencing Reveals Disease Stage-Dependent Transcriptomic Profiles of Regulatory B Cells in Systemic Lupus Erythematosus
    Alajoleen, Razan M.
    Daamen, Andrea
    Timilesena, Prakash R.
    Li, Song
    Lipsky, Peter E.
    Luo, Xin
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [49] Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development
    Bendall, Sean C.
    Davis, Kara L.
    Amir, El-ad David
    Tadmor, Michelle D.
    Simonds, Erin F.
    Chen, Tiffany J.
    Shenfeld, Daniel K.
    Nolan, Garry P.
    Pe'er, Dana
    CELL, 2014, 157 (03) : 714 - 725
  • [50] Characterization of Autoantibody Responses in Thymoma with Myasthenia Gravis by Single-Cell Sequencing of B-cells
    Gomez, A.
    Adamska, J.
    Padda, S.
    Preiss, J.
    Lingampalli, N.
    Wakelee, H.
    Robinson, W.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S1866 - S1867