Single-cell analysis of autoreactive B cells in patients with systemic sclerosis revealed that responses to therapy are determined by effector and regulatory B cell balance

被引：0
|
作者：
Ebata, Satoshi [1 ]
Yoshizaki, Ayumi [1 ]
Fukasawa, Takemichi [1 ]
Sato, Shinichi [1 ]
机构：
[1] Univ Tokyo, Tokyo, Japan
来源：
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
16
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Single-Cell Profiling of Bone Marrow B Cells and Early B Cell Developmental Disorders Associated With Systemic Lupus Erythematosus
    Dong, Chen
    Guo, Yicheng
    Chen, Zechuan
    Li, Teng
    Ji, Juan
    Sun, Chi
    Li, Jing
    Cao, Haixia
    Xia, Yunfei
    Xue, Zhonghui
    Gu, Xixi
    Liang, Qian
    Zhao, Rui
    Fu, Ting
    Ma, Jiaqiang
    Jiang, Shan
    Wu, Chunmei
    Fu, Qiong
    Guo, Genkai
    Bao, Yanfeng
    Guo, Hua
    Yang, Junling
    Xu, Min
    Zhang, Xiaoming
    Sheng, Zizhang
    Gu, Zhifeng
    ARTHRITIS & RHEUMATOLOGY, 2024, 76 (04) : 599 - 613
  • [22] Regulatory B cell imbalance correlates with Tfh expansion in systemic sclerosis
    Ricard, L.
    Malard, F.
    Riviere, S.
    Laurent, C.
    Fain, O.
    Mohty, M.
    Gaugler, B.
    Mekinian, A.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2021, 39 (04) : S20 - S24
  • [23] Analyzing the gene regulatory network in hepatitis B patients by single-cell ATAC sequencing
    Xu, Huixuan
    Yu, Haiyan
    Zheng, Fengping
    Zhang, Cantong
    Cai, Wanxia
    Zhang, Xinzhou
    Tang, Donge
    Dai, Yong
    CLINICAL RHEUMATOLOGY, 2022, 41 (11) : 3513 - 3524
  • [24] Analyzing the gene regulatory network in hepatitis B patients by single-cell ATAC sequencing
    Huixuan Xu
    Haiyan Yu
    Fengping Zheng
    Cantong Zhang
    Wanxia Cai
    Xinzhou Zhang
    Donge Tang
    Yong Dai
    Clinical Rheumatology, 2022, 41 : 3513 - 3524
  • [25] Cytokine-producing B cell balance associated with skin fibrosis in patients with systemic sclerosis
    Horii, M.
    Fushida, N.
    Ikeda, T.
    Hamaguchi, Y.
    Ikawa, Y.
    Komuro, A.
    Matsushita, T.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2022, 142 (12) : S189 - S189
  • [26] SINGLE-CELL DECONVOLUTION OF SKIN FIBROBLAST HETEROGENEITY IN PATIENTS WITH SYSTEMIC SCLEROSIS
    Yan, Q.
    Li, R.
    Lu, L.
    ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 : 1093 - 1093
  • [27] Single cell analysis reveals the autoantigen-reactive B cell cytokine production in systemic sclerosis
    Yoshizaki, A.
    Fukasawa, T.
    Ebata, S.
    Kitamori, T.
    Sato, S.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (05) : S4 - S4
  • [28] BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance
    Matsushita, Takashi
    Kobayashi, Tadahiro
    Mizumaki, Kie
    Kano, Miyu
    Sawada, Tomoyo
    Tennichi, Momoko
    Okamura, Ai
    Hamaguchi, Yasuhito
    Iwakura, Yoichiro
    Hasegawa, Minoru
    Fujimoto, Manabu
    Takehara, Kazuhiko
    SCIENCE ADVANCES, 2018, 4 (07):
  • [29] The role of adjuvant on the regulatory effects of NK cells on B cell responses as revealed by a new model of NK cell deficiency
    Yuan, D
    Bibi, R
    Dang, T
    INTERNATIONAL IMMUNOLOGY, 2004, 16 (05) : 707 - 716
  • [30] More than one antibody of individual B cells revealed by single-cell immune profiling
    Shi, Zhan
    Zhang, Qingyang
    Yan, Huige
    Yang, Ying
    Wang, Pingzhang
    Zhang, Yixiao
    Deng, Zhenling
    Yu, Meng
    Zhou, Wenjing
    Wang, Qianqian
    Yang, Xi
    Mo, Xiaoning
    Zhang, Chi
    Huang, Jing
    Dai, Hui
    Sun, Baofa
    Zhao, Yongliang
    Zhang, Liang
    Yang, Yun-Gui
    Qiu, Xiaoyan
    CELL DISCOVERY, 2019, 5 (1)
12345