Single-cell analysis of autoreactive B cells in patients with systemic sclerosis revealed that responses to therapy are determined by effector and regulatory B cell balance

被引：0
|
作者：
Ebata, Satoshi [1 ]
Yoshizaki, Ayumi [1 ]
Fukasawa, Takemichi [1 ]
Sato, Shinichi [1 ]
机构：
[1] Univ Tokyo, Tokyo, Japan
来源：
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
16
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Single-cell analysis of intrathecal B cells in multiple sclerosis
    Polak, J.
    Lindeman, I.
    Holmoy, T.
    Sollid, L. M.
    Lossius, A.
    MULTIPLE SCLEROSIS JOURNAL, 2018, 24 : 1010 - 1011
  • [2] B cells of multiple sclerosis patients induce autoreactive proinflammatory T cell responses
    Fraussen, Judith
    Claes, Nele
    Van Wijmeersch, Bart
    van Horssen, Jack
    Stinissen, Piet
    Hupperts, Raymond
    Somers, Veerle
    CLINICAL IMMUNOLOGY, 2016, 173 : 124 - 132
  • [3] Effector and regulatory B-cell imbalance in systemic sclerosis: cooperation or competition?
    Liu, Mengguo
    CLINICAL RHEUMATOLOGY, 2024, 43 (09) : 2783 - 2789
  • [4] Single Cell Analysis Revealed That the Response to Cyclophosphamide Therapy Is Regulated By B Cells in Systemic Sclerosis-Associated Interstitial Lung Disease
    Ebata, Satoshi
    Yoshizaki, Ayumi
    Fukasawa, Takemichi
    Nakamura, Kouki
    Hirakawa, Maiko
    Yamashita, Takashi
    Miura, Shunsuke
    Saigusa, Ryosuke
    Hirabayashi, Megumi
    Yoshizaki, Asako
    Akamata, Kaname
    Asano, Yoshihide
    Kazoe, Yutaka
    Mawatari, Kazuma
    Kitamori, Takehiko
    Sato, Shinichi
    ARTHRITIS & RHEUMATOLOGY, 2017, 69
  • [5] Autoreactive B cell responses targeting nuclear antigens in systemic sclerosis: Implications for disease pathogenesis
    Liem, Sophie I. E.
    Neppelenbroek, Sam
    Fehres, Cynthia M.
    Wortel, Corrie
    Toes, Rene E. M.
    Huizinga, Tom W. J.
    Scherer, Hans U.
    Vries-Bouwstra, Jeska K. de
    SEMINARS IN ARTHRITIS AND RHEUMATISM, 2023, 58
  • [6] Effector B Cell Responses in Pediatric Multiple Sclerosis
    Fawaz, Lama M.
    Poupon, Viviane
    Banwell, Brenda
    Piccirillo, Ciro
    Griffiths, Anne
    Silverberg, M.
    Allen, Upton
    Bar-Or, Amit
    NEUROLOGY, 2010, 74 (09) : A7 - A8
  • [7] Role of effector and regulatory B cells in patients with systemic sclerosis: IL-6 producing effector B cells associated with skin fibrosis
    Matsushita, T.
    Kobayashi, T.
    Kano, M.
    Hamaguchi, Y.
    Hasegawa, M.
    Fujimoto, M.
    Takehara, K.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2019, 139 (09) : S222 - S222
  • [8] Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation
    Benjamin Terrier
    Nicolas Derian
    Yoland Schoindre
    Wahiba Chaara
    Guillaume Geri
    Noël Zahr
    Kubéraka Mariampillai
    Michelle Rosenzwajg
    Wassila Carpentier
    Lucile Musset
    Jean-Charles Piette
    Adrien Six
    David Klatzmann
    David Saadoun
    Cacoub Patrice
    Nathalie Costedoat-Chalumeau
    Arthritis Research & Therapy, 14
  • [9] Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation
    Terrier, Benjamin
    Derian, Nicolas
    Schoindre, Yoland
    Chaara, Wahiba
    Geri, Guillaume
    Zahr, Noel
    Mariampillai, Kuberaka
    Rosenzwajg, Michelle
    Carpentier, Wassila
    Musset, Lucile
    Piette, Jean-Charles
    Six, Adrien
    Klatzmann, David
    Saadoun, David
    Patrice, Cacoub
    Costedoat-Chalumeau, Nathalie
    ARTHRITIS RESEARCH & THERAPY, 2012, 14 (05)
  • [10] Comparative analysis of B cell receptor repertoires revealed delay in regulatory B lymphocyte maturation in multiple sclerosis patients
    Lomakin, Y.
    Gabibov, A.
    FEBS OPEN BIO, 2022, 12 : 130 - 130
12345