A convenient and efficient one-pot method for the synthesis of novel acridine-calix[4] arene derivatives as new DNA binding agents via multicomponent reaction

被引：10

作者：

Mirza-Aghayan, Maryam ^{[1
]}

Yarmohammadi, Masoud ^{[1
]}

Zadmard, Reza ^{[1
]}

Boukherroub, Rabah ^{[2
]}

机构：

[1] CCERCI, Tehran, Iran

[2] Univ Lille 1, USR 3078, IRI, F-59658 Villeneuve Dascq, France

来源：

SUPRAMOLECULAR CHEMISTRY | 2014年 / 26卷 / 5-6期

关键词：

DNA binding agent; multicomponent reaction; fluorescence titration; acridine-calix[4]arene derivatives; POTENTIAL ANTITUMOR AGENTS; LARGE CALIXARENE DIMERS; MAJOR GROOVE BINDERS; MOLECULES; 9-ANILINOACRIDINES; INTERCALATORS; RECOGNITION;

D O I：

10.1080/10610278.2013.832763

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new approach is applied for the synthesis of novel acridine-calix[4]arene derivatives via a multicomponent reaction. These compounds have been characterised by H-1 NMR, C-13 NMR and HR-MS. Our binding studies between acridine-functionalised calix[4]arenes and calf thymus DNA (CT-DNA) via fluorescence titration show that these compounds have a good affinity to CT-DNA. A new approach is applied for the synthesis of novel acridine-calix[4]arene derivatives via a multicomponent reaction. These compounds have been characterised by H-1 NMR, C-13 NMR and HR-MS. Our binding studies between acridine-functionalised calix[4]arenes and calf thymus DNA (CT-DNA) via fluorescence titration show that these compounds have a good affinity to CT-DNA.

引用

页码：442 / 449

页数：8

共 50 条

[11] Glycine-Catalyzed Efficient Synthesis of Pyranopyrazoles via One-Pot Multicomponent Reaction
Reddy, M. B. Madhusudana
Jayashankara, V. P.
Pasha, M. A.
SYNTHETIC COMMUNICATIONS, 2010, 40 (19) : 2930 - 2934
[12] Isocyanide-Based Multicomponent Reaction: One-Pot Synthesis of New Derivatives of Iminofuranone
Habibi, Azizollah
Rahmani, Azadeh
HELVETICA CHIMICA ACTA, 2011, 94 (10) : 1806 - 1811
[13] Simple and Efficient Method for Synthesis of Novel 4-Substituted 1-Acylthiosemicarbazides via One-Pot Multicomponent Reactions
Foroughifar, Naser
Mobinikhaledi, Akbar
Moghanian, Hassan
SYNTHETIC COMMUNICATIONS, 2009, 39 (20) : 3668 - 3676
[14] Facile synthesis of tetrahydroquinoline containing dithiocarbamate derivatives via one-pot sequential multicomponent reaction
Senapati, Siddhartha Kumar
Pal, Anit
Das, Animesh
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 22 (20) : 4041 - 4046
[15] Trypsin-catalyzed multicomponent reaction: A novel and efficient one-pot synthesis of thiazole-2-imine derivatives
Zhou, Junbin
Huang, Xingtian
Zhang, Zhuan
Song, Ping
Li, Yiqun
JOURNAL OF BIOTECHNOLOGY, 2017, 241 : 14 - 21
[16] One-pot, multicomponent synthesis under microwave conditions of new imidazole and acridine benzamido acetic acid derivatives
Jazi, Niloofar
Fozooni, Samieh
Hamidian, Hooshang
JOURNAL OF CHEMICAL RESEARCH, 2018, (02) : 80 - 85
[17] An efficient one-pot synthesis of tri-substituted thiophenes via a multicomponent reaction in water
Moghaddam, Firouz Matloubi
Bardajee, Ghasem Rezanejade
Dolabi, Maliheh
JOURNAL OF SULFUR CHEMISTRY, 2010, 31 (05) : 387 - 393
[18] A green, an efficient and viable approach for the synthesis of novel 4H-pyran-indolin-2-one derivatives via a one-pot reaction by grinding method
Prasanna, Bolla Lakshmi
Rao, Battula Sreenivasa
Lavanya, Palakondu
Maddila, Suresh
CHEMICAL DATA COLLECTIONS, 2022, 37
[19] Microwave-Assisted Synthesis of New Spiro[indoline-3,4'-quinoline] Derivatives via a One-Pot Multicomponent Reaction
Zhu, Song-Lei
Zhao, Kai
Su, Xiao-Ming
Ji, Shun-Jun
SYNTHETIC COMMUNICATIONS, 2009, 39 (08) : 1355 - 1366
[20] A multicomponent reaction for the one-pot synthesis of 4-aza-2,3-didehydropodophyllotoxin and derivatives
Tratrat, C
Giorgi-Renault, S
Husson, HP
ORGANIC LETTERS, 2002, 4 (19) : 3187 - 3189

← 1 2 3 4 5 →