Nickel-Catalyzed Arylboration of Alkenylarenes: Synthesis of Boron-Substituted Quaternary Carbons and Regiodivergent Reactions

被引：53

作者：

Chen, Liang-An ^{[1
]}

Lear, Alan R. ^{[1
]}

Gao, Pin ^{[2
]}

Brown, M. Kevin ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, 800 E Kirkwood Ave, Bloomington, IN 47405 USA

[2] Xi An Jiao Tong Univ, MOE Key Lab Nonequilibrium Synth & Modulat Conden, Xian Key Lab Sustainable Energy Mat Chem, Dept Chem,Sch Sci, Xian 710049, Shaanxi, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2019年 / 58卷 / 32期

基金：

美国国家卫生研究院;

关键词：

alkenes; arylboration; boron; cross coupling; nickel; ENANTIOSELECTIVE SYNTHESIS; CONJUGATE BORATION; REGIOSELECTIVE ARYLBORATION; ASYMMETRIC-SYNTHESIS; TERTIARY; ESTERS; CARBOBORATION; ALKENES; HYDROBORATION; BORYLATION;

D O I：

10.1002/anie.201904861

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method for the construction of boron-substituted quaternary carbons or diarylquaternary carbons by arylboration of highly substituted alkenylarenes is presented. A wide range of alkenes and arylbromides can participate in this reaction thus allowing for a diverse assortment of products to be prepared. In addition, a solvent dependent regiodivergent arylboration of 1,2-disubstituted alkenylarenes is presented, thus greatly increasing the scope of products that can be accessed.

引用

页码：10956 / 10960

页数：5

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