Assessment of human antihuman antibodies to eculizumab after long-term treatment in patients with paroxysmal nocturnal hemoglobinuria

被引:14
|
作者
Hillmen, Peter [1 ]
Muus, Petra [2 ]
Szer, Jeffrey [3 ,4 ]
Hill, Anita [5 ]
Hoechsmann, Britta [6 ,7 ]
Kulasekararaj, Austin
Risitano, Antonio M. [8 ,9 ]
Van Den Neste, Eric [10 ]
Liljeholm, Maria [11 ]
Ebrahim, Kurt S. [12 ]
Bedrosian, Camille L. [13 ]
Gao, Xiang [13 ]
Ames, Donna [13 ]
Socie, Gerard [14 ]
机构
[1] St James Univ Hosp, Sect Expt Haematol, Level 6,Wellcome Trust Brenner Bldg,Beckett St, Leeds LS9 7TF, W Yorkshire, England
[2] Radboud Univ Nijmegen, Med Ctr, Dept Hematol, NL-6525 ED Nijmegen, Netherlands
[3] Royal Melbourne Hosp, Dept Clin Haematol, Melbourne, Vic, Australia
[4] Royal Melbourne Hosp, BMT Serv, Melbourne, Vic, Australia
[5] Leeds Teaching Hosp, St James Inst Oncol, Dept Haematol, Leeds, W Yorkshire, England
[6] Univ Ulm, Inst Clin Transfus Med & Immunogenet Ulm, Inst Transfus Med, German Red Cross Blood Transfus Serv Baden Wurtte, D-89069 Ulm, Germany
[7] Univ Hosp Ulm, Ulm, Germany
[8] Kings Coll Hosp London, London, England
[9] Univ Naples Federico II, Dipartimento Med Clin & Chirurg, Naples, Italy
[10] Clin Univ UCL St Luc, Dept Hematol, Brussels, Belgium
[11] Univ Umea Hosp, Dept Hematol, S-90185 Umea, Sweden
[12] New England Canc Specialists, Scarborough, ME USA
[13] Alex Pharmaceut Inc, Cheshire, CT USA
[14] Hosp St Louis, AP HP Hematol, Paris, France
关键词
COMPLEMENT INHIBITOR ECULIZUMAB; IMMUNOGENICITY;
D O I
10.1002/ajh.24280
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E16 / E17
页数:2
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