Clozapine pharmacokinetics studied with CYP1A2 knockout mice

被引:0
|
作者
Aitchison, KJ [1 ]
Jann, MW [1 ]
Wolff, K [1 ]
Sakai, T [1 ]
Makoff, AJ [1 ]
Collier, DA [1 ]
Gonzalez, FJ [1 ]
Kerwin, RW [1 ]
机构
[1] Inst Psychiat, Dept Psychol Med, Sect Clin Neuropharmacol, London SE5 8AF, England
关键词
D O I
10.1016/S0920-9964(00)90889-2
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
B164
引用
收藏
页码:235 / 235
页数:1
相关论文
共 50 条
  • [41] A preliminary study of microbiome changes in Cyp1a2(+/+) wild type and Cyp1a2(-/-) mice following gestational and lactational exposure to a PCB mixture
    Curran, Christine Perdan
    Dickson, Pamela
    Brinkman, Nick
    Caudill, Shelby
    Cooper, Joshua
    NEUROTOXICOLOGY AND TERATOLOGY, 2018, 67 : 86 - 86
  • [42] Use of CYP1A2 (-/-) knockout and CYP1A2 (+/+) C57BL/6N parental strains of mice to compare metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
    Diliberto, JJ
    Hakk, H
    TOXICOLOGICAL SCIENCES, 2003, 72 : 363 - 363
  • [43] Pharmacokinetics of caffeine in plasma and saliva, and the influence of caffeine abstinence on CYP1A2 metrics
    Perera, Vidya
    Gross, Annette S.
    Xu, Hongmei
    McLachlan, Andrew J.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2011, 63 (09) : 1161 - 1168
  • [44] Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity
    Härtter, S
    Nordmark, A
    Rose, DM
    Bertilsson, L
    Tybring, G
    Laine, K
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 56 (06) : 679 - 682
  • [45] Effect of CYP1A2 polymorphism on the pharmacokinetics of agomelatine in Chinese healthy male volunteers
    Song, L.
    Du, Q.
    Jiang, X.
    Wang, L.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2014, 39 (02) : 204 - 209
  • [46] Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine
    Backman, Janne T.
    Schroder, Marika T.
    Neuvonen, Pertti J.
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 64 (01) : 17 - 24
  • [47] Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine
    Janne T. Backman
    Marika T. Schröder
    Pertti J. Neuvonen
    European Journal of Clinical Pharmacology, 2008, 64 : 17 - 24
  • [48] Treatment-resistance to clozapine in association with ultrarapid CYP1A2 activity and the C→A polymorphism in intron 1 of the CYP1A2 gene:: Effect of grapefruit juice and low-dose fluvoxamine
    Özdemir, V
    Kalow, W
    Okey, AB
    Lam, MSM
    Albers, LJ
    Reist, C
    Fourie, J
    Posner, P
    Collins, EJ
    Roy, R
    JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2001, 21 (06) : 603 - 607
  • [49] Association between CYP1A2 polymorphisms and clozapine-induced adverse reactions in patients with schizophrenia
    Ferrari, Marco
    Bolla, Emilio
    Bortolaso, Paola
    Callegari, Camilla
    Poloni, Nicola
    Lecchini, Sergio
    Vender, Simone
    Marino, Franca
    Cosentino, Marco
    PSYCHIATRY RESEARCH, 2012, 200 (2-3) : 1014 - 1017
  • [50] CYP1A2 activity predicts the clozapine steady-state concentration in schizophrenic patients.
    Özdemir, V
    Posner, P
    Collins, EJ
    Walker, SE
    Roy, R
    Walkes, W
    Tang, BK
    Kennedy, JL
    McKenzie, J
    Kalow, W
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1999, 65 (02) : 175 - 175