Clozapine pharmacokinetics studied with CYP1A2 knockout mice

被引:0
|
作者
Aitchison, KJ [1 ]
Jann, MW [1 ]
Wolff, K [1 ]
Sakai, T [1 ]
Makoff, AJ [1 ]
Collier, DA [1 ]
Gonzalez, FJ [1 ]
Kerwin, RW [1 ]
机构
[1] Inst Psychiat, Dept Psychol Med, Sect Clin Neuropharmacol, London SE5 8AF, England
关键词
D O I
10.1016/S0920-9964(00)90889-2
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
B164
引用
收藏
页码:235 / 235
页数:1
相关论文
共 50 条
  • [21] CYP1A2 genotype affects carbamazepine pharmacokinetics in children with epilepsy
    Djordjevic, Natasa
    Milovanovic, Dragana Dragas
    Radovanovic, Marija
    Radosavljevic, Ivan
    Obradovic, Slobodan
    Jakovljevic, Mihajlo
    Milovanovic, Dragan
    Milovanovic, Jasmina R.
    Jankovic, Slobodan
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2016, 72 (04) : 439 - 445
  • [22] Role of CYP1A2 in hepatic sequestration of dioxin: Studies using CYP1A2 knock-out mice
    Diliberto, JJ
    Burgin, D
    Birnbaum, LS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 236 (02) : 431 - 433
  • [23] CYP1A2 genotype affects carbamazepine pharmacokinetics in children with epilepsy
    Natasa Djordjevic
    Dragana Dragas Milovanovic
    Marija Radovanovic
    Ivan Radosavljevic
    Slobodan Obradovic
    Mihajlo Jakovljevic
    Dragan Milovanovic
    Jasmina R. Milovanovic
    Slobodan Jankovic
    European Journal of Clinical Pharmacology, 2016, 72 : 439 - 445
  • [24] Effects of Mexiletine, a CYP1A2 Inhibitor, on Tizanidine Pharmacokinetics and Pharmacodynamics
    Momo, Kenji
    Homma, Masato
    Osaka, Yoshiko
    Inomata, Shin-ichi
    Tanaka, Makoto
    Kohda, Yukinao
    JOURNAL OF CLINICAL PHARMACOLOGY, 2010, 50 (03): : 331 - 337
  • [25] Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice
    Liang, HCL
    McKinnon, RA
    Nebert, DW
    BIOCHEMICAL PHARMACOLOGY, 1997, 54 (10) : 1127 - 1131
  • [26] Uroporphyria in mice: Thresholds for hepatic CYP1A2 and iron
    Gorman, N
    Ross, KL
    Walton, HS
    Bement, WJ
    Szakacs, JG
    Gerhard, GS
    Dalton, TP
    Nebert, DW
    Eisenstein, RS
    Sinclair, JF
    Sinclair, PR
    HEPATOLOGY, 2002, 35 (04) : 912 - 921
  • [27] Association of the haplotypes of CYP1A2 gene on clozapine metabolism in Chinese psychotic patients
    Chen, T-T
    Chen, J. -Y.
    Yen, C. -F
    Chang, W. -H.
    Liou, Y. -J.
    Hsich, H-Y.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2008, 11 : 252 - 253
  • [28] Added value of CYP1A2 phenotyping in teenager patients on clozapine: a case report
    Rodieux, F. J.
    Berney, P.
    Desmeules, J.
    Besson, M.
    SWISS MEDICAL WEEKLY, 2014, 144 : 50S - 51S
  • [29] 4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice
    Tsuneoka, Y
    Dalton, TP
    Miller, ML
    Clay, CD
    Shertzer, HG
    Talaska, G
    Medvedovic, M
    Nebert, DW
    JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2003, 95 (16) : 1227 - 1237
  • [30] Evidence from a population pharmacokinetics analysis for a major effect of CYP1A2 activity on inter- and intraindividual variations of clozapine clearance
    Dailly, E
    Urien, S
    Chanut, E
    Claudel, B
    Guerra, N
    Fernandez, C
    Jolliet, P
    Bourin, M
    PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2002, 26 (04): : 699 - 703