Blood homocysteine and kidney involvement in type 1 and type 2 diabetes mellitus

被引：0
|
作者：
Giampietro, O [1 ]
Calvi, D [1 ]
Forotti, G [1 ]
Boldrini, E [1 ]
Marchini, F [1 ]
Moretti, L [1 ]
Matteucci, E [1 ]
机构：
[1] Univ Pisa, Dipartimento Med Interna, Pisa, Italy
来源：
ATHEROSCLEROSIS: RISK FACTORS, DIAGNOSIS, AND TREATMENT | 2002年
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In 215 diabetics (52 type 1, 163 type 2) patients and 60 healthy controls, tHcy was measured to check the relationships between renal status and metabolic parameters. While tHcy resulted significantly higher in micromacroalbuminuric diabetics, compared to normoalbuminurics (14.3 +/- 84.7 vs 11.1 +/- 20.3 mumol/l, p 0.002) and in low-GFR (less than or equal to 70 ml/min) versus normal -GFR patients (16.2 +/- 7.9 vs 10.3 +/- 4.2 ml/min, respectively p < 0.0001), serum creatinine and GFR proved to be the main determinants of tHcy levels in diabetics as just proved in non-diabetic people.
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页码：209 / 212
页数：4
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