Photobactericidal activity of methylene blue derivatives against vancomycin-resistant Enterococcus spp.

被引：72
|
作者：
Wainwright, M [1 ]
Phoenix, DA
Gaskell, M
Marshall, B
机构：
[1] Univ Cent Lancashire, Photochemotherapy Grp, Dept Biol Sci, Preston PR1 2HE, Lancs, England
[2] Royal Preston Hosp, Publ Hlth Lab, Preston PR2 4HT, Lancs, England
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1999年 / 44卷 / 06期
关键词：
D O I：
10.1093/jac/44.6.823
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The toxicities and phototoxicities of methylene blue and its two methylated derivatives were measured against one standard and three vancomycin-resistant pathogenic strains of Enterococcus spp, Each of the compounds was bactericidal and the derivatives exhibited photobactericidal activity on illumination at a 'light' dose of 6.3 J/cm(2) against one or more of the strains, Increased bactericidal and photobactericidal activity in the methylated derivatives is thought to be due to their higher hydrophobicities allowing greater interaction with the bacterial cell wall, In addition, the derivatives exhibited higher inherent photosensitizing efficacies.
引用
收藏
页码：823 / 825
页数：3
相关论文
共 50 条
  • [21] Galangin synergistically revives the antibacterial activity of vancomycin against vancomycin-resistant Enterococcus faecium
    Ayamuang, Intu-orn
    Teethaisong, Yothin
    Sirichaiwetchakoon, Kittipot
    Suknasang, Siriporn
    Watthana, Santi
    Chaiseha, Yupaporn
    Eumkeb, Griangsak
    JOURNAL OF APPLIED MICROBIOLOGY, 2025, 136 (01)
  • [22] Survival of Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus spp. for an Extended Period of Transport
    Robinson, Gwen L.
    Harris, Anthony D.
    Morgan, Daniel J.
    Pineles, Lisa
    Belton, Beverly M.
    Johnson, J. Kristie
    JOURNAL OF CLINICAL MICROBIOLOGY, 2012, 50 (07) : 2466 - 2468
  • [23] VANA-MEDIATED VANCOMYCIN-RESISTANT ENTEROCOCCUS SPP IN SEWAGE
    TORRES, C
    REGUERA, JA
    SANMARTIN, MJ
    PEREZDIAZ, JC
    BAQUERO, F
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1994, 33 (03) : 553 - 561
  • [24] In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci
    Pospisilova, Sarka
    Michnova, Hana
    Kauerova, Tereza
    Pauk, Karel
    Kollar, Peter
    Vinsova, Jarmila
    Imramovsky, Ales
    Cizek, Alois
    Jampilek, Josef
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (12) : 2184 - 2188
  • [25] BACTERICIDAL ACTIVITY OF VANCOMYCIN, DAPTOMYCIN, AMPICILLIN AND AMINOGLYCOSIDES AGAINST VANCOMYCIN-RESISTANT ENTEROCOCCUS-FAECIUM
    BINGEN, E
    LAMBERTZECHOVSKY, N
    LECLERCQ, R
    DOIT, C
    MARIANIKURKDJIAN, P
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1990, 26 (05) : 619 - 626
  • [26] Characterization of hospital-associated Vancomycin-resistant Enterococcus spp. in a tertiary care center in Hessen
    Englert, K.
    Ehrhart, A.
    Werner, G.
    Kempf, V. A. J.
    Brandt, C.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2011, 301 : 101 - 101
  • [27] Vancomycin-resistant Enterococcus faecalis
    Branley, J
    Yan, B
    Benn, RAV
    MEDICAL JOURNAL OF AUSTRALIA, 1996, 165 (05) : 292 - 292
  • [28] Control of vancomycin-resistant enterococcus
    Lai, KK
    ANNALS OF INTERNAL MEDICINE, 1997, 126 (12) : 1000 - 1001
  • [29] Vancomycin-resistant Enterococcus faecium
    Marovac, J
    Campos, MI
    REVISTA MEDICA DE CHILE, 2000, 128 (06) : 685 - 686
  • [30] Reporting antimicrobial susceptibilities and phenotypes of resistance to vancomycin in vancomycin-resistant Enterococcus spp. clinical isolates: A nationwide proficiency study
    Fernandez-Cuenca, Felipe
    Lopez-Hernandez, Inmaculada
    Cercenado, Emilia
    Conejo, Maria Carmen
    Tormo, Nuria
    Gimeno, Concepcion
    Pascual, Alvaro
    ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA, 2023, 41 (06): : 335 - 341
12345