The authors report the presence of high titer antibodies to glutamic acid decarboxylase (anti-GAD65) until age 24 months in two asymptomatic newborns of a woman with stiff-person syndrome (SPS). No signs of SPS were detectable in the two children at ages 6 and 8 years. This observation indicates that other cofactors are involved in the pathogenesis of SPS.
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Curtin Univ, Kent St, Perth, WA, Australia
Royal Melbourne Hosp, Dept Neurol, Melbourne, Vic, AustraliaCurtin Univ, Kent St, Perth, WA, Australia
Seneviratne, Sinali O.
Buzzard, Katherine A.
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Royal Melbourne Hosp, Dept Neurol, Melbourne, Vic, Australia
Monash Univ, Fac Med Nursing & Hlth Sci, Eastern Hlth Clin Sch, Box Hill Hosp, Box Hill, Melbourne, Vic, AustraliaCurtin Univ, Kent St, Perth, WA, Australia
Buzzard, Katherine A.
Cruse, Belinda
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Royal Melbourne Hosp, Dept Neurol, Melbourne, Vic, AustraliaCurtin Univ, Kent St, Perth, WA, Australia
Cruse, Belinda
Monif, Mastura
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Royal Melbourne Hosp, Dept Neurol, Melbourne, Vic, Australia
Alfred Hlth, Dept Neurol, Melbourne, Vic, Australia
Univ Melbourne, Dept Physiol, Melbourne, Vic, Australia
Monash Univ, Dept Neurosci, Melbourne, Vic, AustraliaCurtin Univ, Kent St, Perth, WA, Australia