Methemoglobinemia Induced by Lidocaine-Prilocaine Cream

被引：1

作者：

Shamriz, Oded ^{[1
]}

Cohen-Glickman, Inbal ^{[3
]}

Reif, Shimon ^{[1
]}

Shteyer, Eyal ^{[1
,2
]}

机构：

[1] Hadassah Hebrew Univ, Med Ctr, Dept Pediat, IL-91120 Jerusalem, Israel

[2] Hadassah Hebrew Univ, Med Ctr, Pediat Gastroenterol Unit, IL-91120 Jerusalem, Israel

[3] Hebrew Univ Jerusalem, Sch Pharm, Div Clin Pharm, IL-91905 Jerusalem, Israel

来源：

ISRAEL MEDICAL ASSOCIATION JOURNAL | 2014年 / 16卷 / 04期

关键词：

EMLA; methemoglobinemia; lidocaine-prilocaine; seizures; BENZOCAINE-INDUCED METHEMOGLOBINEMIA; TOPICAL APPLICATION; CNS TOXICITY; EMLA CREAM; INFANT; ANESTHESIA; ANALGESIA;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

With growing awareness of the importance of pain control in all procedures, the use of lidocaine-prilocaine cream (EMLA) for all ages is increasing. Lidocaine-prilocaine cream has been implicated as a cause of methemoglobinemia. Diagnostic clues my be oxygen-resistant cyanosis and an oxygen "saturation gap" between arterial blood saturation and pulse oximetry. Treatment with intravenous Methylene blue is often effective. Since EMLA is often mistakenly considered risk-free it is routinely applied by medical staff in the emergency room. Subsequent to the case of EMLA-induced methemoglobinemia in an year old girl we wish to alert the medical community to this phenomenon, and in this work review the relevant literature.

引用

页码：250 / 254

页数：5

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