Methemoglobinemia Induced by Lidocaine-Prilocaine Cream

被引：1
|
作者：
Shamriz, Oded [1 ]
Cohen-Glickman, Inbal [3 ]
Reif, Shimon [1 ]
Shteyer, Eyal [1 ,2 ]
机构：
[1] Hadassah Hebrew Univ, Med Ctr, Dept Pediat, IL-91120 Jerusalem, Israel
[2] Hadassah Hebrew Univ, Med Ctr, Pediat Gastroenterol Unit, IL-91120 Jerusalem, Israel
[3] Hebrew Univ Jerusalem, Sch Pharm, Div Clin Pharm, IL-91905 Jerusalem, Israel
来源：
ISRAEL MEDICAL ASSOCIATION JOURNAL | 2014年 / 16卷 / 04期
关键词：
EMLA; methemoglobinemia; lidocaine-prilocaine; seizures; BENZOCAINE-INDUCED METHEMOGLOBINEMIA; TOPICAL APPLICATION; CNS TOXICITY; EMLA CREAM; INFANT; ANESTHESIA; ANALGESIA;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
With growing awareness of the importance of pain control in all procedures, the use of lidocaine-prilocaine cream (EMLA) for all ages is increasing. Lidocaine-prilocaine cream has been implicated as a cause of methemoglobinemia. Diagnostic clues my be oxygen-resistant cyanosis and an oxygen "saturation gap" between arterial blood saturation and pulse oximetry. Treatment with intravenous Methylene blue is often effective. Since EMLA is often mistakenly considered risk-free it is routinely applied by medical staff in the emergency room. Subsequent to the case of EMLA-induced methemoglobinemia in an year old girl we wish to alert the medical community to this phenomenon, and in this work review the relevant literature.
引用
收藏
页码：250 / 254
页数：5
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