共 50 条
- [41] Discovery of 4-azaindoles as novel inhibitors of c-Met kinaseBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (10) : 2780 - 2784Porter, John论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandLumb, Simon论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandFranklin, Richard J.论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandGascon-Simorte, Jose M.论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandCalmiano, Mark论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandLe Riche, Kelly论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandLallemand, Benedicte论文数: 0 引用数: 0 h-index: 0机构: UCB Pharma, R&D, B-1420 Braine Lalleud, Belgium UCB Celltech, Slough SL1 3WE, Berks, EnglandKeyaerts, Jean论文数: 0 引用数: 0 h-index: 0机构: UCB Pharma, R&D, B-1420 Braine Lalleud, Belgium UCB Celltech, Slough SL1 3WE, Berks, EnglandEdwards, Helen论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandMaloney, Alison论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandDelgado, Jean论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandKing, Lloyd论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandFoley, Anne论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandLecomte, Fabien论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandReuberson, James论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandMeier, Christoph论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, EnglandBatchelor, Mark论文数: 0 引用数: 0 h-index: 0机构: UCB Celltech, Slough SL1 3WE, Berks, England UCB Celltech, Slough SL1 3WE, Berks, England
- [42] MEDI 317-Discovery of potent, selective and orally active TRPV1 antagonists for the relief of painABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232Nakao, Kazunari论文数: 0 引用数: 0 h-index: 0机构: Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, Japan Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, JapanNagayama, Satoshi论文数: 0 引用数: 0 h-index: 0机构: Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, Japan Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, JapanShishido, Yuji论文数: 0 引用数: 0 h-index: 0机构: Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, Japan Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, JapanHirano, Misato论文数: 0 引用数: 0 h-index: 0机构: Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, Japan Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, JapanSudo, Masaki论文数: 0 引用数: 0 h-index: 0机构: Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, Japan Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, JapanTakada, Junji论文数: 0 引用数: 0 h-index: 0机构: Pfizer Japan Inc, Discovery Biol Res, Global Res & Dev, Aichi, Japan Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, JapanKanai, Yoshihito论文数: 0 引用数: 0 h-index: 0机构: Pfizer Japan Inc, Discovery Biol Res, Global Res & Dev, Aichi, Japan Pfizer Japan Inc, Discovery Chem Res, Global Res & Dev, Aichi, Japan
- [43] MEDI 352-Discovery of novel FMS kinase inhibitors as anti-inflammatory agentsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 236Meegalla, Sanath K.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAIllig, Carl R.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAChen, Jinsheng论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAWall, Mark J.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAWilson, Kenneth J.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USABallentine, Shelley K.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USARudolph, M. Jonathan论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USADesJarlais, Renee L.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAChan, Yanmin论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USASchubert, Carsten论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAPetrounia, Ioanna论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USACrysler, Carl S.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAMolloy, Christopher J.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAChaikin, Margery A.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAManthey, Carl L.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USAPlayer, Mark R.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USATomczuk, Bruce E.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA Johnson & Johnson Pharmaceut Res & Dev, Spring House, PA 19477 USA
- [44] MEDI 454-Discovery and SAR of orally active tri- and tetracyclic mGluR1 antagonistsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234Burnett, Duane A.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USATulshian, Deen论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USACooke, Stephanie论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAMatasi, Julius论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAKorakas, Peter论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USASilverman, Lisa S.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USASasikumar, Thavalakulamgara K.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAWu, Wen-Lian论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USABennett, Chad论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAKnutson, Chad论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAGreenlee, William J.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAReggiani, A.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAVeltri, A.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USABertorelli, R.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAFredduzzi, S.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USALozza, G.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USATarozzo, G.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAFoglia, C.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAGrilli, M.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USA
- [45] MEDI 126-Discovery of tricyclic pyrazoles as potent checkpoint-1 kinase inhibitorsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232Tong, Yunsong论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USAClaiborne, Akiyo论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USATao, Zhi-Fu论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, Canc Res, Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USAKovar, Peter论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, Canc Res, Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USAPark, Chang论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, Canc Res, Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USAChen, Zehan论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, Canc Res, Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USACredo, R. Bruce论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, D47B, Canc Res, Pharmaceut Prod Div, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USAStewart, Kent D.论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USAZhang, Haiying论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USARosenberg, Saul论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, R460, Canc Res, GPRD, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USASham, Hing L.论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USASowin, Thomas论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, Canc Res, Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USALin, Nan-Horng论文数: 0 引用数: 0 h-index: 0机构: Abbott Labs, D 47B, Abbott Pk, IL 60064 USA Abbott Labs, R47B, Canc Res, GPRD, Abbott Pk, IL 60064 USA
- [46] MEDI 134-Discovery of orally active mGluR1 receptor antagonists for the treatment of chronic painABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234Cooke, Stephanie论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAKorakas, Peter论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USASilverman, Lisa S.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAMatasi, Julius论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USATulshian, Deen论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USABurnett, Duane论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAGreenlee, William J.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USA Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAReggiani, A.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAVeltri, A.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USABertorelli, R.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USADowney, P.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAFredduzzi, S.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAGrilli, M.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USANicolussi, E.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USALozza, G.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAForlani, G.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAPetro, R.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USALiporati, V.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USATarozzo, G.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAContib, S.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USAFoglia, C.论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Res Inst, Dept Neurobiol Res, Milan, Italy Schering Plough Res Inst, CV CNS, Dept Chem Res, Kenilworth, NJ 07033 USA
- [47] MEDI 16-Discovery of 2-acylindoles as potent, orally active human glucagon receptor antagonistsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235Sinz, Christopher J.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USABittner, Amy论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAKim, Ronald M.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USABrady, Ed论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Pharmacol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USACandelore, Mari Rios论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USADing, Victor D-H.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAJiang, Guoquiang论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USALin, Zhen论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USALins, Ashley Rouse论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAMcCann, Peggy论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Pharmacol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAMiller, Corin论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Res Imaging, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USANam, Kiyean论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Mol Syst, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAQureshi, Sajjad A.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USASalituro, Gino论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USASaperstein, Richard论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Pharmacol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAShang, Jackie论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Drug Metab, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USASzalkowski, Deborah论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USATota, Laurie论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAWright, Michael论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAWang, Regina论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Drug Metab, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAXu, Shiyao论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Drug Metab, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAYang, Xiaodong论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAZhang, Bei论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Metab Disorders Mol Endocrinol, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAHammond, Milton论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USATata, James论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USAParmee, Emma论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA Merck & Co Inc, Dept Med Chem, Rahway, NJ 07065 USA
- [48] Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic StabilityJOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (19) : 9228 - 9242Patel, Leena论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAChandrasekhar, Jayaraman论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAEvarts, Jerry论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Acerta Pharma, 15400 SE 30th Pl,Suite 206, Bellevue, WA 98007 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAForseth, Kristen论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAHaran, Aaron C.论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAIp, Carmen论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAKashishian, Adam论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAKim, Musong论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAKoditek, David论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAKoppenol, Sandy论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USALad, Latesh论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USALepist, Eve-Irene论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAMcGrath, Mary E.论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAPerreault, Stephane论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAPuri, Kamal D.论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Celgene Corp, 10300 Campus Point Dr,Suite 100, San Diego, CA 92121 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAVillasenor, Armando G.论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USASomoza, John R.论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USASteiner, Bart H.论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USATherrien, Joseph论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USATreiberg, Jennifer论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USAPhillips, Gary论文数: 0 引用数: 0 h-index: 0机构: Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA Gilead Sci Inc, 333 Lakeside Dr, Foster City, CA 94404 USA
- [49] Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase γ InhibitorsJOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (11) : 5467 - 5482Leahy, James W.论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USABuhr, Chris A.论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAJohnson, Henry W. B.论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAKim, Byung Gyu论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USABaik, TaeGon论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USACannoy, Jonah论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAForsyth, Timothy P.论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAJeong, Joon Won论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USALee, Matthew S.论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAMa, Sunghoon论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USANoson, Kevin论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAWang, Longcheng论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAWilliams, Matthew论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USANuss, John M.论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USABrooks, Eric论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAFoster, Paul论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAGoon, Leanne论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAHeald, Nathan论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAHolst, Charles论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAJaeger, Christopher论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USALam, Scott论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USALougheed, Julie论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USALam Nguyen论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAPlonowski, Arthur论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USASong, Joanne论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAStout, Thomas论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAWu, Xiang论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAYakes, Michael F.论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAYu, Peiwen论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USAZhang, Wentao论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USALamb, Peter论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USARaeber, Olivia论文数: 0 引用数: 0 h-index: 0机构: Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA Exelixis, Dept Drug Discovery, San Francisco, CA 94083 USA
- [50] In vivo characterization and mechanism of action of orally active Aurora kinase/VEGFR inhibitorsCANCER RESEARCH, 2009, 69Fang, Li论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USASho, Angela论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USAHsu, Nancy论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USAAurrecoechea, Natalia论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USARobinson, Louise论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USASimon, Reyna论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USAKelson, Andrew论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USALaborde, Edgardo论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USACheng, Mingshan论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USAKeck, James论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USACai, Danying论文数: 0 引用数: 0 h-index: 0机构: Telik Inc, Palo Alto, CA USA Telik Inc, Palo Alto, CA USA