Inhibition of Fibroblast Growth Factor-23 (FGF-23) Rescues Bone and Hematopoietic Stem Cell Niche Defects in BetaThalassemia, Uncovering the Missing Link between Hematopoiesis and Bone

被引:1
|
作者
Aprile, Annamaria [1 ]
Raggi, Laura [1 ]
Bolamperti, Simona [2 ]
Storto, Mariangela [1 ]
Villa, Isabella [2 ]
Morello, Gaia [3 ]
Marktel, Sarah [4 ]
Tripodo, Claudio [3 ]
Motta, Irene [5 ,6 ]
Cappellini, Maria Domenica [5 ,6 ]
Rubinacci, Alessandro
Ferrari, Giuliana [7 ]
机构
[1] IRCCS San Raffaele Sci Inst, San Raffaele Telethon Inst Gene Therapy SR Tiget, Milan, Italy
[2] IRCCS San Raffaele Sci Inst, Osteoporosis & Bone & Mineral Metab Unit, Milan, Italy
[3] Univ Palermo, Human Pathol Sect, Dept Hlth Sci, Tumor Immunol Unit, Palermo, Italy
[4] IRCCS San Raffaele Sci Inst, Hematol & Bone Marrow Transplantat Unit, Milan, Italy
[5] Univ Milan, Dept Clin Sci & Community, Milan, Italy
[6] IRCCS Ca Granda Fdn, Maggiore Policlin Hosp, Milan, Italy
[7] Univ Vita Salute San Raffaele, Milan, Italy
关键词
D O I
10.1182/blood-2021-148366
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
572
引用
收藏
页数:3
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