Cytotoxic effects of sesquiterpene lactones from the flowers of Hemisteptia lyrata B

被引：40
|
作者：
Ha, TJ
Jang, DS
Lee, JR
Lee, KD
Lee, J
Hwang, SW
Jung, HJ
Nam, SH
Park, KH
Yang, MS [1 ]
机构：
[1] Gyeongsang Natl Univ, Div Appl Sci, Dept Agr Chem, Chinju 660701, South Korea
[2] Gyeongsang Natl Univ, Inst Agr & Life Sci, Chinju 660701, South Korea
[3] Ewha Womans Univ, Grad Sch Mol Life Sci, Seoul 120750, South Korea
[4] Chinju Natl Univ, Dept Food Proc, Chinju 660758, South Korea
来源：
ARCHIVES OF PHARMACAL RESEARCH | 2003年 / 26卷 / 11期
关键词：
Hemisteptia lyrata Bunge; sesquiterpene lactone; aguerin B; 8 alpha-acetoxyzaluzanin C; cynaropicrin; deacylcynaropicrin; cytotoxic activity;
D O I：
10.1007/BF02980201
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Four guaia-12,6-olide type sesquiterpene lactones, aguerin B (1), 8alpha-acetoxyzaluzanin C (2), cynaropicrin (3), and deacylcynaropicrin (4), were isolated from the flowers of Hemisteptia lyrata Bunge. It is the first report on the isolation of compounds 1-4 from Hemisteptia species. All the isolates (1-4) were examined for their cytotoxic activity against SK-OV-3, LOX-IMVI, A549, MCF-7, PC-3, and HCT-15 human cancer cell lines.
引用
收藏
页码：925 / 928
页数：4
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