Cytotoxic effects of sesquiterpene lactones from the flowers of Hemisteptia lyrata B

被引：40
|
作者：
Ha, TJ
Jang, DS
Lee, JR
Lee, KD
Lee, J
Hwang, SW
Jung, HJ
Nam, SH
Park, KH
Yang, MS [1 ]
机构：
[1] Gyeongsang Natl Univ, Div Appl Sci, Dept Agr Chem, Chinju 660701, South Korea
[2] Gyeongsang Natl Univ, Inst Agr & Life Sci, Chinju 660701, South Korea
[3] Ewha Womans Univ, Grad Sch Mol Life Sci, Seoul 120750, South Korea
[4] Chinju Natl Univ, Dept Food Proc, Chinju 660758, South Korea
来源：
ARCHIVES OF PHARMACAL RESEARCH | 2003年 / 26卷 / 11期
关键词：
Hemisteptia lyrata Bunge; sesquiterpene lactone; aguerin B; 8 alpha-acetoxyzaluzanin C; cynaropicrin; deacylcynaropicrin; cytotoxic activity;
D O I：
10.1007/BF02980201
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Four guaia-12,6-olide type sesquiterpene lactones, aguerin B (1), 8alpha-acetoxyzaluzanin C (2), cynaropicrin (3), and deacylcynaropicrin (4), were isolated from the flowers of Hemisteptia lyrata Bunge. It is the first report on the isolation of compounds 1-4 from Hemisteptia species. All the isolates (1-4) were examined for their cytotoxic activity against SK-OV-3, LOX-IMVI, A549, MCF-7, PC-3, and HCT-15 human cancer cell lines.
引用
收藏
页码：925 / 928
页数：4
相关论文
共 50 条
  • [31] Cytotoxic sesquiterpene lactones from the aerial parts of Inula aucheriana
    Gohari, Ahmad Reza
    Mosaddegh, Mahmoud
    Naghibi, Farzaneh
    Eslami-Tehrani, Bahara
    Pirani, Atefeh
    Hamzeloo-Moghadam, Maryam
    Read, Roger W.
    ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS, 2015, 87 (02): : 777 - 785
  • [32] Sesquiterpene lactones from Centaurea spinosa and their antibacterial and cytotoxic activities
    Saroglou, V
    Karioti, A
    Demetzos, C
    Dimas, K
    Skaltsa, H
    JOURNAL OF NATURAL PRODUCTS, 2005, 68 (09): : 1404 - 1407
  • [33] Sesquiterpene Lactones with potent cytotoxic activities from Vernonia chinensis
    Chen, X
    Zhan, ZJ
    Zhang, XW
    Ding, J
    Yue, JM
    PLANTA MEDICA, 2005, 71 (10) : 949 - 954
  • [34] Cytotoxic sesquiterpene lactones from Centaurothamnus maximus and Vicoa pentanema
    Muhammad, W
    Takamatsu, S
    Mossa, JS
    El-Feraly, FS
    Walker, LA
    Clark, AM
    PHYTOTHERAPY RESEARCH, 2003, 17 (02) : 168 - 173
  • [35] Cytotoxic sesquiterpene lactones from Campuloclinium macrocephalum (=Eupatorium macrocephalum)
    Pereira Cabral, Marcia R.
    Cecchetto, Mariana
    Batista, Joao M., Jr.
    Batista, Andrea N. L.
    Foglio, Mary Ann
    Tasca Gois Ruiz, Ana Lucia
    Barrotto do Carmo, Marta R.
    da Costa, Willian Ferreira
    Baldoqui, Debora C.
    Sarragiotto, Maria H.
    PHYTOCHEMISTRY, 2020, 179
  • [36] Cytotoxic sesquiterpene lactones from Vernonia pachyclada from the Madagascar rainforest
    Williams, RB
    Norris, A
    Slebodnick, C
    Merola, J
    Miller, JS
    Andriantsiferana, R
    Rasamison, VE
    Kingston, DGI
    JOURNAL OF NATURAL PRODUCTS, 2005, 68 (09): : 1371 - 1374
  • [37] Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide type linear sesquiterpene lactones from Anthemis auriculata
    Karioti, A.
    Skaltsa, H.
    Kaiser, M.
    Tasdemir, D.
    PLANTA MEDICA, 2009, 75 (09) : 965 - 965
  • [38] Sesquiterpene lactones from Inula britannica and their cytotoxic and apoptotic effects on human cancer cell lines
    Bai, NS
    Lai, CS
    He, K
    Zhou, Z
    Zhang, L
    Quan, Z
    Zhu, NQ
    Zheng, QY
    Pan, MH
    Ho, CT
    JOURNAL OF NATURAL PRODUCTS, 2006, 69 (04): : 531 - 535
  • [39] SESQUITERPENE LACTONES AND FLAVONOIDS IN FLOWERS OF TANACETUM-VULGARE
    OGNYANOV, I
    TODOROVA, M
    PLANTA MEDICA, 1983, 48 (03) : 181 - 183
  • [40] Cytotoxic sesquiterpene lactones of Egyptian Tanacetum santolinoides
    Youssef, Diaa T. A.
    Ramadan, Mahmoud A.
    Ibrahim, Sabrin R. M.
    Badr, Jihan M.
    NATURAL PRODUCT COMMUNICATIONS, 2007, 2 (08) : 795 - 798
12345