Exudative Retinal Detachment Following Chimeric Antigen Receptor T-Cell Therapy in Relapsed B-Cell Acute Lymphoblastic Leukemia

Chimeric antigen receptor (CAR) T-cell therapy has become a novel approach in the treat-ment of many hematologic malignancies. However, ocular adverse effects have not been well described. This report presents a case of a pediatric patient with relapsed B-cell acute lymphoblastic leukemia with ocular involvement treated with CAR T-cell therapy who developed an exudative retinal de-tachment likely secondary to an inflammatory re-sponse to CAR T-cell therapy.