Exudative Retinal Detachment Following Chimeric Antigen Receptor T-Cell Therapy in Relapsed B-Cell Acute Lymphoblastic Leukemia

被引：3

作者：

Khanna, Saira ^{[1
]}

Mackin, Anna G. ^{[1
]}

Dao, David T. ^{[1
]}

Komati, Rahul ^{[2
]}

Morocco, Perry C. ^{[3
]}

LaBelle, James L. ^{[4
]}

Shah, Hassan A. ^{[1
]}

Blair, Michael P. ^{[1
,5
]}

机构：

[1] Univ Chicago, Dept Ophthalmol & Visual Sci, Chicago, IL 60637 USA

[2] Georgia Retina, Atlanta, GA USA

[3] Univ Chicago, Comer Childrens Hosp, Dept Pediat, Chicago, IL 60637 USA

[4] Univ Chicago, Dept Pediat, Corner Childrens Hosp, Sect Hematol Oncol Stem Cell Transplantat, Chicago, IL 60637 USA

[5] Retina Consultants Ltd, 2454 E Dempster St,Suite 400, Des Plaines, IL 60016 USA

来源：

OPHTHALMIC SURGERY LASERS & IMAGING RETINA | 2022年 / 53卷 / 02期

关键词：

D O I：

10.3928/23258160-20220124-01

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Chimeric antigen receptor (CAR) T-cell therapy has become a novel approach in the treat-ment of many hematologic malignancies. However, ocular adverse effects have not been well described. This report presents a case of a pediatric patient with relapsed B-cell acute lymphoblastic leukemia with ocular involvement treated with CAR T-cell therapy who developed an exudative retinal de-tachment likely secondary to an inflammatory re-sponse to CAR T-cell therapy.

引用

页码：113 / 115

页数：3

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