Transplantation of allogenic cells in the therapy of patients with dilated cardiomyopathy

被引：9

作者：

Kirillov, A. M. ^{[1
]}

Fatkhudinov, T. Kh. ^{[1
]}

Dyachkov, A. V. ^{[1
]}

Koroteev, A. V. ^{[1
]}

Goldshtein, D. V. ^{[1
]}

Bochkov, N. P. ^{[1
]}

机构：

[1] ReMeTeks Co, Russian Acad Sci, B V Petrovskii Russian Res Surg Ctr, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2007年 / 144卷 / 04期

关键词：

skeletal myoblasts; multipotent stromal cells; allogenic transplantation; dilated cardiomyopathy;

D O I：

10.1007/s10517-007-0392-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We carried out a pilot study on intracoronary transplantation of prenatal allogenic skeletal myoblasts and multipotent bone marrow stromal cells to patients with dilated cardiomyopathy. Intracoronary transplantation of allogenic cells is a feasible and safe procedure: there were no life-threatening rhythm and conduction disturbances, symptoms of hemodynamic instability, and thromboembolic complications. Positive clinical effect of cell transplantation persisted for 6 months and consisted in decreased content of brain natriuretic peptide and improved tolerance to physical exercises. We observed no reliable dynamics of the major echocardiographic parameters and their correlations with patient's status.

引用

页码：635 / 639

页数：5

共 50 条

[31] Barriers to cardiac transplantation in idiopathic dilated cardiomyopathy: The Washington, DC dilated cardiomyopathy study
Coughlin, SS
Halabi, S
Metayer, C
CIRCULATION, 1996, 94 (08) : 4043 - 4043
[32] Barriers to cardiac transplantation in idiopathic dilated cardiomyopathy: The Washington, DC, dilated cardiomyopathy study
Coughlin, SS
Halabi, S
Metayer, C
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, 1998, 90 (06) : 342 - 348
[33] Genetic basis of familial dilated cardiomyopathy patients undergoing heart transplantation
Cuenca, Sofia
Ruiz-Cano, Maria J.
Ramon Gimeno-Blanes, Juan
Jurado, Alfonso
Salas, Clara
Gomez-Diaz, Iria
Padron-Barthe, Laura
Javier Grillo, Jose
Vilches, Carlos
Segovia, Javier
Pascual-Figal, Domingo
Lara-Pezzi, Enrique
Monserrat, Lorenzo
Alonso-Pulpon, Luis
Garcia-Pavia, Pablo
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2016, 35 (05): : 625 - 635
[34] The predictors of the response to cardiac resynchronization therapy in patients with dilated cardiomyopathy
Manca, P.
Cossa, S.
Tola, G. F.
Scalone, A.
Schintu, B.
Setzu, A.
Mameli, S.
Sanna, N.
Giardina, A.
Minerba, L.
Matta, G.
Porcu, M. Maurizio
EUROPEAN JOURNAL OF HEART FAILURE, 2017, 19 : 436 - 436
[35] Advances in heart failure therapy in pediatric patients with dilated cardiomyopathy
Stefan Rupp
Christian Jux
Heart Failure Reviews, 2018, 23 : 555 - 562
[36] Immunoadsorption Therapy Reduces Oxidative Stress in Patients With Dilated Cardiomyopathy
Kashima, Yuichiro
Kasai, Hiroki
Izawa, Atsushi
Miyashita, Yusuke
Kumazaki, Setsuo
Koyama, Jun
Takahashi, Masafumi
Yazaki, Yoshikazu
Higuchi, Makoto
Ikeda, Uichi
CIRCULATION, 2009, 120 (18) : S907 - S907
[37] Advances in heart failure therapy in pediatric patients with dilated cardiomyopathy
Rupp, Stefan
Jux, Christian
HEART FAILURE REVIEWS, 2018, 23 (04) : 555 - 562
[38] EFFECT AND COMPLICATIONS OF CHRONIC AMRINONE THERAPY IN PATIENTS WITH DILATED CARDIOMYOPATHY
CORBALAN, R
CASANEGRA, P
MEZZANO, D
MARINOVIC, I
CHAMORRO, G
RODRIGUEZ, J
VALENZUELA, P
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1984, 3 (02) : 471 - 471
[39] Can β-blocker therapy be withdrawn from patients with dilated cardiomyopathy?
Morimoto, S
Shimizu, K
Yamada, K
Hiramitsu, S
Hishida, H
AMERICAN HEART JOURNAL, 1999, 138 (03) : 456 - 459
[40] Intracoronary Versus Transendocardial Stem Cell Transplantation in Patients With Dilated Cardiomyopathy
Vrtovec, Bojan
Poglajen, Gregor
Lezaic, Luka
Domanovic, Dragoslav
Haddad, Francois
CIRCULATION, 2011, 124 (21)

← 1 2 3 4 5 →