Transplantation of allogenic cells in the therapy of patients with dilated cardiomyopathy

被引：9
|
作者：
Kirillov, A. M. [1 ]
Fatkhudinov, T. Kh. [1 ]
Dyachkov, A. V. [1 ]
Koroteev, A. V. [1 ]
Goldshtein, D. V. [1 ]
Bochkov, N. P. [1 ]
机构：
[1] ReMeTeks Co, Russian Acad Sci, B V Petrovskii Russian Res Surg Ctr, Moscow, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2007年 / 144卷 / 04期
关键词：
skeletal myoblasts; multipotent stromal cells; allogenic transplantation; dilated cardiomyopathy;
D O I：
10.1007/s10517-007-0392-4
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We carried out a pilot study on intracoronary transplantation of prenatal allogenic skeletal myoblasts and multipotent bone marrow stromal cells to patients with dilated cardiomyopathy. Intracoronary transplantation of allogenic cells is a feasible and safe procedure: there were no life-threatening rhythm and conduction disturbances, symptoms of hemodynamic instability, and thromboembolic complications. Positive clinical effect of cell transplantation persisted for 6 months and consisted in decreased content of brain natriuretic peptide and improved tolerance to physical exercises. We observed no reliable dynamics of the major echocardiographic parameters and their correlations with patient's status.
引用
收藏
页码：635 / 639
页数：5
相关论文
共 50 条
  • [21] Feasibility of bone marrow stromal cells autologous transplantation for dilated cardiomyopathy
    Cheng Zhou
    Chenyuan Yang
    Shiliang Xiao
    Hongwen Fei
    Journal of Huazhong University of Science and Technology, 2007, 27 : 75 - 78
  • [22] Feasibility of bone marrow stromal cells autologous transplantation for dilated cardiomyopathy
    Zhou Cheng
    Yang Chenyuan
    Xiao Shiliang
    Fei Hongwen
    JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES, 2007, 27 (01) : 75 - 78
  • [23] VASODILATOR THERAPY OF DILATED CARDIOMYOPATHY
    COHN, JN
    POSTGRADUATE MEDICAL JOURNAL, 1986, 62 (728) : 599 - 600
  • [24] HEART-TRANSPLANTATION FOR DILATED CARDIOMYOPATHY
    ADWANI, SS
    WHITEHEAD, BF
    REES, PG
    WHITMORE, P
    FABRE, JW
    ELLIOTT, MJ
    DELEVAL, MR
    ARCHIVES OF DISEASE IN CHILDHOOD, 1995, 73 (05) : 447 - 452
  • [25] Immunoadsorption therapy in dilated cardiomyopathy
    Felix, Stephan B.
    Beug, Daniel
    Doerr, Marcus
    EXPERT REVIEW OF CARDIOVASCULAR THERAPY, 2015, 13 (02) : 145 - 152
  • [26] Cell therapy in dilated cardiomyopathy
    Mathur, A.
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2016, 46 : 26 - 26
  • [27] Heart transplantation in chemotherapeutic dilated cardiomyopathy
    Grande, AM
    Rinaldi, M
    Sinelli, S
    D'Armini, AM
    Vigano, M
    TRANSPLANTATION PROCEEDINGS, 2003, 35 (04) : 1516 - 1518
  • [28] Heart Transplantation in Women With Dilated Cardiomyopathy
    Regitz-Zagrosek, Vera
    Petrov, George
    Lehmkuhl, Elke
    Smits, Jaqueline M.
    Babitsch, Birgit
    Brunhuber, Claudia
    Jurmann, Beate
    Stein, Julia
    Schubert, Carola
    Merz, Noel Bairey
    Lehmkuhl, Hans Brendan
    Hetzer, Roland
    TRANSPLANTATION, 2010, 89 (02) : 236 - 244
  • [29] Familial dilated cardiomyopathy in patients transplanted for idiopathic dilated cardiomyopathy
    Monserrat, L
    Hermida, M
    Bouzas, B
    Mosquera, I
    Mahon, N
    Peteiro, J
    Alvarez, N
    Penas-Lado, M
    Crespo, M
    Castro-Beiras, A
    REVISTA ESPANOLA DE CARDIOLOGIA, 2002, 55 (07): : 725 - 732
  • [30] TRANSPLANTATION OF AUTOLOGOUS BONE MARROW CELLS, IMPROVE THE EJECTION FRACTION IN PATIENTS WITH DILATED CARDIOMYOPATHY OF DIVERSE ETIOLOGY
    Bartolucci, J.
    Carrion, F.
    Lamich, R.
    Pedreros, P.
    Verdugo, F.
    Salazar, L.
    Khoury, M.
    Figueroa, F.
    CYTOTHERAPY, 2013, 15 (04) : S30 - S31
12345