Synthesis of Benzocycloheptanones through Coupling of δ,ε-Unsaturated Chromium Carbene Complexes and 2-Alkynylbenzoyl Derivatives

被引：9
|
作者：
Patti, Rajesh Kumar [1 ]
Waynant, Kristopher V. [1 ]
Herndon, James W. [1 ]
机构：
[1] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA
来源：
ORGANIC LETTERS | 2011年 / 13卷 / 11期
关键词：
CYCLOADDITION CHEMISTRY; PRODUCT DISTRIBUTION; POTENT ANTAGONISTS; CHIRAL AUXILIARY; CYCLIZATION; RECEPTORS; ALDEHYDES; RHENIUM; SYSTEMS;
D O I：
10.1021/ol200825j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The coupling of pentenylcarbene complexes and 2-alkynylbenzoyl derivatives affords naphthocycloheptanones in a single step involving simultaneous construction of both the seven-membered ring and one of the aromatic rings. Aryl tethered systems undergo intramolecular cyclopropanation.
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页码：2848 / 2851
页数：4
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