Synthesis of Benzocycloheptanones through Coupling of δ,ε-Unsaturated Chromium Carbene Complexes and 2-Alkynylbenzoyl Derivatives

被引：9

作者：

Patti, Rajesh Kumar ^{[1
]}

Waynant, Kristopher V. ^{[1
]}

Herndon, James W. ^{[1
]}

机构：

[1] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 11期

关键词：

CYCLOADDITION CHEMISTRY; PRODUCT DISTRIBUTION; POTENT ANTAGONISTS; CHIRAL AUXILIARY; CYCLIZATION; RECEPTORS; ALDEHYDES; RHENIUM; SYSTEMS;

D O I：

10.1021/ol200825j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The coupling of pentenylcarbene complexes and 2-alkynylbenzoyl derivatives affords naphthocycloheptanones in a single step involving simultaneous construction of both the seven-membered ring and one of the aromatic rings. Aryl tethered systems undergo intramolecular cyclopropanation.

引用

页码：2848 / 2851

页数：4

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