Differential uptake of myo-inositol in vivo into rat brain areas

被引：35
|
作者：
Patishi, Y
Lubrich, B
Berger, M
Kofman, O
vanCalker, D
Belmaker, RH
机构：
[1] BEN GURION UNIV NEGEV,FAC HLTH SCI,MINIST HLTH,MENTAL HLTH CTR,BEER SHEVA,ISRAEL
[2] KLINIKUM UNIV FREIBURG,ABT ALLGEMEINE PSYCHIAT POLIKLIN,FREIBURG,GERMANY
来源：
EUROPEAN NEUROPSYCHOPHARMACOLOGY | 1996年 / 6卷 / 01期
关键词：
inositol; uptake; brain areas;
D O I：
10.1016/0924-977X(95)00061-S
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Oral inositol has been reported to have antidepressant and antipanic properties in humans. Inositol enters the brain poorly and high doses are required. Natural uptake processes and specific transporters are involved. We here report that intraperitoneally administered inositol is taken up differently by various brain areas and that brain areas have different baseline inositol levels. These effects could be important in understanding the differential effects of lithium-induced lowering of inositol and of behavioral effects of exogenous inositol.
引用
收藏
页码：73 / 75
页数：3
相关论文
共 50 条
  • [21] Myo-inositol: with or without
    Carlomagno, Gianfranco
    Unfer, Vittorio
    Benvenga, Salvatore
    Nestler, John E.
    ENDOCRINE JOURNAL, 2015, 62 (03) : 297 - 298
  • [22] Osmoregulatory alterations in myo-inositol uptake by bovine lens epithelial cells .5. Mechanism of the myo-inositol efflux pathway
    Reeves, RE
    Cammarata, PR
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1996, 37 (04) : 619 - 629
  • [23] Brain Myo-Inositol in Depressive Bipolar Patients Treated with Oral Inositol
    Alfonso Ontiveros, Jose
    Trevino, Edgar
    Gil, Alfonso
    BIOLOGICAL PSYCHIATRY, 2012, 71 (08) : 197S - 198S
  • [24] Myo-Inositol content determined by myo-inositol biosynthesis and oxidation in blueberry fruit
    Song, Fangyuan
    Su, Hongyan
    Yang, Nan
    Zhu, Luying
    Cheng, Jieshan
    Wang, Lei
    Cheng, Xianhao
    FOOD CHEMISTRY, 2016, 210 : 381 - 387
  • [25] MYO-INOSITOL PHOSPHATES FROM BEEF BRAIN PHOSPHOINOSITIDE
    GRADO, C
    BALLOU, CE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1960, 235 (06) : PC23 - PC24
  • [26] Screening for inhibitors of human brain myo-inositol monophosphatase
    Ganzhorn, AJ
    Brunati, C
    Kugel, C
    Islam, K
    Galvan, M
    Chanal, MC
    Stefanelli, S
    Sponga, F
    Andreini, P
    Wolf, E
    Piriou, F
    Dulery, B
    Verne, J
    Lamard, M
    Wagner, J
    Danzin, C
    NEW FRONTIERS IN SCREENING FOR MICROBIAL BIOCATALYSTS, 1998, 53 : 103 - 109
  • [27] METABOLISM OF C-14 MYO-INOSITOL IN THE RAT
    MOSCATELLI, EA
    LARNER, J
    FEDERATION PROCEEDINGS, 1957, 16 (01) : 223 - 223
  • [28] Does myo-inositol oxygenase, the only enzyme to catalyze myo-inositol in vivo, play a role in the etiology of polycystic ovarian syndrome?
    Mertoglu, Cuma
    Gunay, Murat
    Gul, Vahdet
    Kulhan, Mehmet
    Aktas, Mehmet
    Coban, Taha Abdulkadir
    GYNECOLOGICAL ENDOCRINOLOGY, 2018, 34 (05) : 418 - 421
  • [29] Effects of myo-Inositol ingestion on human brain myo-inositol levels: A proton magnetic resonance spectroscopic imaging study
    Moore, CM
    Breeze, JL
    Kukes, TJ
    Rose, SL
    Dager, SR
    Cohen, BM
    Renshaw, PF
    BIOLOGICAL PSYCHIATRY, 1999, 45 (09) : 1197 - 1202
  • [30] FORMATION OF FREE AND LIPID MYO-INOSITOL IN INTACT RAT
    HAUSER, G
    BIOCHIMICA ET BIOPHYSICA ACTA, 1963, 70 (03) : 278 - &
12345