Differential uptake of myo-inositol in vivo into rat brain areas

被引：35
|
作者：
Patishi, Y
Lubrich, B
Berger, M
Kofman, O
vanCalker, D
Belmaker, RH
机构：
[1] BEN GURION UNIV NEGEV,FAC HLTH SCI,MINIST HLTH,MENTAL HLTH CTR,BEER SHEVA,ISRAEL
[2] KLINIKUM UNIV FREIBURG,ABT ALLGEMEINE PSYCHIAT POLIKLIN,FREIBURG,GERMANY
来源：
EUROPEAN NEUROPSYCHOPHARMACOLOGY | 1996年 / 6卷 / 01期
关键词：
inositol; uptake; brain areas;
D O I：
10.1016/0924-977X(95)00061-S
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Oral inositol has been reported to have antidepressant and antipanic properties in humans. Inositol enters the brain poorly and high doses are required. Natural uptake processes and specific transporters are involved. We here report that intraperitoneally administered inositol is taken up differently by various brain areas and that brain areas have different baseline inositol levels. These effects could be important in understanding the differential effects of lithium-induced lowering of inositol and of behavioral effects of exogenous inositol.
引用
收藏
页码：73 / 75
页数：3
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