Novel series of CB2 selective antagonists for the treatment of autoimmune disorders: Synthesis, functional evaluation and ligand-steered modeling

被引:0
|
作者
Phatak, Sharangdhar S.
Petrov, Ravil R.
Astruc-Diaz, Fanny
Cavasotto, Claudio N.
Diaz, Philippe
机构
[1] Univ Texas Hlth Sci Ctr Houston, Sch Hlth Informat Sci, Houston, TX USA
[2] Univ Montana, Dept Biomed & Pharmaceut Sci, Missoula, MT 59812 USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 240卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
111-MEDI
引用
收藏
页数:1
相关论文
共 50 条
  • [11] Synthesis, pharmacological evaluation and docking studies of pyrrole structure-based CB2 receptor antagonists
    Ragusa, Giulio
    Gomez-Canas, Maria
    Morales, Paula
    Hurst, Dow P.
    Deligia, Francesco
    Pazos, Ruth
    Pinna, Gerard A.
    Fernandez-Ruiz, Javier
    Goya, Pilar
    Reggio, Patricia H.
    Jagerovic, Nadine
    Garcia-Arencibia, Moises
    Murineddu, Gabriele
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 101 : 651 - 667
  • [12] Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain
    Gleave, Robert J.
    Beswick, Paul J.
    Brown, Andrew J.
    Giblin, Gerard M. P.
    Goldsmith, Paul
    Haslam, Carl P.
    Mitchell, William L.
    Nicholson, Neville H.
    Page, Lee W.
    Patel, Sadhana
    Roomans, Susan
    Slingsby, Brian P.
    Swarbrick, Martin E.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (02) : 465 - 468
  • [13] Part 1: Synthesis and SAR evaluation of modified imidazoheterocycles - novel CB1/CB2 agonists
    Beckett, R. P.
    Ralbovsky, J. L.
    Luo, R.
    Cowan, C. L.
    Foster, R.
    Henault, C.
    Shelekhin, T.
    Rakhilina, L.
    Abriola, L.
    Gardell, L. R.
    Labissiere, G.
    Spencer, R. H.
    Menzaghi, F.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [14] In vitro and in vivo pharmacological characterization of JTE907, a novel selective ligand for cannabinoid CB2 receptor
    Iwamura, H
    Suzuki, H
    Ueda, Y
    Kaya, T
    Inaba, T
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2001, 296 (02): : 420 - 425
  • [15] Synthesis and testing of novel classical cannabinoids: Exploring the side chain ligand binding pocket of the CB1 and CB2 receptors
    Nadipuram, AK
    Krishnamurthy, M
    Ferreira, AM
    Li, W
    Moore, BM
    BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 11 (14) : 3121 - 3132
  • [16] Synthesis and biological evaluation of a ring analogs of the selective CB2 inverse agonist SMM-189
    Alghamdi, Sahar S.
    Mustafa, Suni M.
    Moore, Bob M., II
    BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 33
  • [17] Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands
    Bertini, Simone
    Parkkari, Teija
    Savinainen, Juha R.
    Arena, Chiara
    Saccomanni, Giuseppe
    Saguto, Simone
    Ligresti, Alessia
    Allara, Marco
    Bruno, Agostino
    Marinelli, Luciana
    Di Marzo, Vincenzo
    Novellino, Ettore
    Manera, Clementina
    Macchia, Marco
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 90 : 526 - 536
  • [18] Synthesis and biological evaluation of a novel series of GPER antagonists for the treatment of gallstone formation
    DeLeon, Chelsea
    Arnatt, Christopher
    Wang, David Q. -H.
    Wilhelm, McKenna
    Sweeney, Patrick
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [19] Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists
    Tai, Chia-Liang
    Hung, Ming-Shiu
    Pawar, Vijay D.
    Tseng, Shi-Liang
    Song, Jen-Shin
    Hsieh, Wan-Ping
    Chiu, Hua-Hao
    Wu, Hui-Chuan
    Hsieh, Min-Tsang
    Kuo, Chun-Wei
    Hsieh, Chia-Chien
    Tsao, Jing-Po
    Chao, Yu-Sheng
    Shia, Kak-Shan
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2008, 6 (03) : 447 - 450
  • [20] Synthesis and in vitro evaluation of novel 2-oxo-1,2-dihydroquinoline CB2 receptor inverse agonists
    Raitio, Katri H.
    Savinainen, Juha R.
    Nevalainen, Tapio
    Jarvinen, Tomi
    Vepsalainen, Jouko
    CHEMICAL BIOLOGY & DRUG DESIGN, 2006, 68 (06) : 334 - 340