A water-soluble two-photon ratiometric triarylboron probe with nucleolar targeting by preferential RNA binding

被引：49

作者：

Liu, Jun ^{[1
,2
]}

Zhang, Shilu ^{[1
,2
]}

Zhang, Chenghua ^{[1
,2
]}

Dong, Jun ^{[1
,2
]}

Shen, Chengyi ^{[1
,2
]}

Zhu, Jiang ^{[1
,2
]}

Xu, Huajun ^{[3
]}

Fu, Mingkai ^{[4
]}

Yang, Guoqiang ^{[5
]}

Zhang, Xiaoming ^{[6
]}

机构：

[1] North Sichuan Med Coll, Sch Preclin Med, Sichuan Key Lab Med Imaging, Nanchong 637000, Peoples R China

[2] North Sichuan Med Coll, Sch Preclin Med, Dept Chem, Nanchong 637000, Peoples R China

[3] Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China

[4] Chinese Acad Sci, Inst Elect Engn, Beijing 100190, Peoples R China

[5] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, Key Lab Photochem, Beijing 100190, Peoples R China

[6] North Sichuan Med Coll, Affiliated Hosp, Nanchong 637000, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 83期

关键词：

FLUORESCENT-PROBES; LIVING CELLS; CYTOPLASM; COMPOUND; COMPLEX;

D O I：

10.1039/c7cc06045a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

By functionalizing triarylboron with cyclen, we developed a two-photon fluorescence probe, TAB-2, which can selectively bind RNA with a ratiometric readout. We tested TAB-2 in NIH/3T3 fibroblast cells, and demonstrated its capability in visualizing nucleoli and analyzing microenvironment polarity by two-photon and fluorescence-lifetime imaging microscopy.

引用

页码：11476 / 11479

页数：4

共 50 条

[41] Synthesis and characterization of water-soluble two-photon excited blue fluorescent chromophores for bioimaging
Ali Hayek
Frédéric Bolze
Jean-François Nicoud
Patrice L. Baldeck
Yves Mély
Photochemical & Photobiological Sciences, 2006, 5 : 102 - 106
[42] Water-Soluble Polythiophene for Two-Photon Excitation Fluorescence Imaging and Photodynamic Therapy of Cancer
Lan, Minhuan
Zhao, Shaojing
Xie, Yusheng
Zhao, Junfang
Guo, Liang
Niu, Guangle
Li, Ying
Sun, Hongyan
Zhang, Hongyan
Liu, Weimin
Zhang, Jinyuan
Wang, Pengfei
Zhang, Wenjun
ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (17) : 14590 - 14595
[43] Protein-induced fluorescence enhancement of two-photon excitable water-soluble diketopyrrolopyrroles
Tang, Simon
Zadeh, Ebrahim H. Ghazvini
Kim, Bosung
Toomey, Nikia T.
Bondar, Mykhailo V.
Belfield, Kevin D.
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 15 (31) : 6511 - 6519
[44] Water-soluble [2.2]paracyclophane chromophores with large two-photon action cross sections
Woo, HY
Hong, JW
Liu, B
Mikhailovsky, A
Korystov, D
Bazan, GC
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (03) : 820 - 821
[45] A theoretical study of a series of water-soluble triphenylamine photosensitizers for two-photon photodynamic therapy
Wang, Xin
Yin, Xue
Lai, Xiao-Yong
Liu, Ying-Tao
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2018, 203 : 229 - 235
[46] Water-soluble red fluorescent protein dimers for hypoxic two-photon photodynamic therapy
Feng, Wan
Qian, Ying
JOURNAL OF MATERIALS CHEMISTRY B, 2024, 12 (09) : 2413 - 2424
[47] Study on water-soluble benzylidene cyclopentanone dyes for two-photon induced photodynamic therapy
Yang W.
Zou Q.
Zhou Y.
Gu Y.
Zhao Y.
Wu F.
Guangxue Xuebao/Acta Optica Sinica, 2011, 31 (SUPPL.1):
[48] Water-Soluble Conjugated Polymers for Amplification of One- and Two-photon Properties of Photosensitizers
He, Fang
Ren, Xinsheng
Shen, Xiaoqin
Xu, Qing-Hua
MACROMOLECULES, 2011, 44 (13) : 5373 - 5380
[49] Observation of inflammation-induced mitophagy during stroke by a mitochondria-targeting two-photon ratiometric probe
Cheng, Fei
Qiang, Taotao
Ren, Longfang
Liang, Tianyu
Gao, Xiaoyang
Wang, Baoshuai
Hu, Wei
ANALYST, 2021, 146 (08) : 2632 - 2637
[50] Construction of a ratiometric two-photon fluorescent probe to monitor the changes of mitochondrial viscosity
Ren, Mingguang
Zhou, Kai
Wang, Li
Liu, Keyin
Lin, Weiying
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 262 : 452 - 459

← 1 2 3 4 5 →