Facile Synthesis of 5-Carboxamide-oxazolines via a Passerini 3CC-Staudinger-aza-Wittig Sequence

被引：18
|
作者：
Wu, Jing [1 ]
Liu, Jian-Chao [1 ]
Wang, Long [1 ]
Ding, Ming-Wu [1 ]
机构：
[1] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China
来源：
SYNLETT | 2011年 / 19期
基金：
中国国家自然科学基金;
关键词：
oxazoline; Passerini reaction; aza-Wittig reaction; Staudinger reaction; iminophosphorane; UGI 4-COMPONENT REACTION; AZA-WITTIG REACTION; EFFICIENT SYNTHESIS; MULTICOMPONENT REACTIONS; BIOLOGICAL EVALUATION; INHIBITORS; ISOCYANIDE; ANALOGS; POTENT;
D O I：
10.1055/s-0031-1289865
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Carboxamide-oxazolines were synthesized via a Passerini 3CC-Staudinger-aza-Wittig sequence in moderate to good yields, starting from easily accessible chloroacetaldehyde, isocyanides, and various acids.
引用
收藏
页码：2880 / 2882
页数：3
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