Facile Synthesis of 5-Carboxamide-oxazolines via a Passerini 3CC-Staudinger-aza-Wittig Sequence

被引：18

作者：

Wu, Jing ^{[1
]}

Liu, Jian-Chao ^{[1
]}

Wang, Long ^{[1
]}

Ding, Ming-Wu ^{[1
]}

机构：

[1] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China

来源：

SYNLETT | 2011年 / 19期

基金：

中国国家自然科学基金;

关键词：

oxazoline; Passerini reaction; aza-Wittig reaction; Staudinger reaction; iminophosphorane; UGI 4-COMPONENT REACTION; AZA-WITTIG REACTION; EFFICIENT SYNTHESIS; MULTICOMPONENT REACTIONS; BIOLOGICAL EVALUATION; INHIBITORS; ISOCYANIDE; ANALOGS; POTENT;

D O I：

10.1055/s-0031-1289865

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Carboxamide-oxazolines were synthesized via a Passerini 3CC-Staudinger-aza-Wittig sequence in moderate to good yields, starting from easily accessible chloroacetaldehyde, isocyanides, and various acids.

引用

页码：2880 / 2882

页数：3

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