First stereoselective synthesis of the versatile chiral building block (7aR)-5,6-dihydro-7a-methyl-1H-indene-2,7(4H,7aH)-dione

被引：0
|
作者：
Wei, ZL [1 ]
Li, ZY [1 ]
Lin, GQ [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2000年 / 12期
关键词：
asymmetric synthesis; microbial reduction; ketols; bicyclic compounds; Wieland-Miescher ketone analog;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A versatile chiral building block (7aR)-5,6-dihydro-7a-methyl-1H-indene-2,7(4H,7aH)-dione (4) was firstly enantiomerically synthesized from the microbial transformation ketol product 6 in 61.3% overall yield and over 96% ee.
引用
收藏
页码：1673 / 1676
页数：4
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