First stereoselective synthesis of the versatile chiral building block (7aR)-5,6-dihydro-7a-methyl-1H-indene-2,7(4H,7aH)-dione

被引：0

作者：

Wei, ZL ^{[1
]}

Li, ZY ^{[1
]}

Lin, GQ ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2000年 / 12期

关键词：

asymmetric synthesis; microbial reduction; ketols; bicyclic compounds; Wieland-Miescher ketone analog;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A versatile chiral building block (7aR)-5,6-dihydro-7a-methyl-1H-indene-2,7(4H,7aH)-dione (4) was firstly enantiomerically synthesized from the microbial transformation ketol product 6 in 61.3% overall yield and over 96% ee.

引用

页码：1673 / 1676

页数：4

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