Aggregation-Induced Emission Materials that Aid in Pharmaceutical Research

被引：25

作者：

Wang, Bingnan ^{[1
]}

Liu, Shanshan ^{[1
]}

Liu, Xiaolin ^{[2
,3
]}

Hu, Rong ^{[1
]}

Qin, Anjun ^{[1
]}

Tang, Ben Zhong ^{[1
,2
,3
,4
]}

机构：

[1] South China Univ Technol, State Key Lab Luminescent Mat & Devices, Guangdong Prov Key Lab Luminescence Mol Aggregate, Ctr Aggregat Induced Emiss, Guangzhou 510640, Peoples R China

[2] Hong Kong Univ Sci & Technol, Dept Chem, Hong Kong Branch,Inst Adv Study,Kowloon, Chinese Natl Engn Res Ctr Tissue Restorat & Recon, Clear Water Bay, Hong Kong 999077, Peoples R China

[3] Hong Kong Univ Sci & Technol, Dept Chem & Biol Engn, Kowloon, Clear Water Bay, Hong Kong 999077, Peoples R China

[4] Chinese Univ Hong Kong, Shenzhen Inst Mol Aggregate Sci & Engn, Sch Sci & Engn, 2001 Longxiang Blvd, Shenzhen 518172, Guangdong, Peoples R China

来源：

ADVANCED HEALTHCARE MATERIALS | 2021年 / 10卷 / 24期

基金：

中国国家自然科学基金;

关键词：

aggregation-induced emission; AIE bioactive agents; AIE carriers; AIE prodrugs; drug delivery; ACTIVE THERANOSTIC AGENT; PRODRUG; DESIGN; CANCER; FLUORESCENCE; DELIVERY; PHOTOSENSITIZERS; DISCRIMINATION; POLYMERIZATION; VISUALIZATION;

D O I：

10.1002/adhm.202101067

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The in situ visualization of drugs can improve the understanding of their pharmacokinetics and mechanisms. Aggregation-induced emission (AIE) materials, which can aid in the visualization of drugs, are gradually being employed in pharmaceutical research due to their excellent fluorescence properties, good biocompatibility, and extremely high sensitivity. Herein, the progress of AIE materials in pharmaceutical research, including AIE carriers for drug delivery, AIE multifunctional prodrugs, and AIE compounds as bioactive reagents for theranostics is briefly described. Moreover, the opportunities and challenges of AIE materials in pharmaceutical research are discussed in depth. It is believed that versatile AIE materials hold great promise for the promotion of pharmacological research and can facilitate significant advancements in clinical fields.

引用

页数：18

共 50 条

[31] Utilization of aggregation-induced emission materials in urinary system diseases
Xu, Haodong
Chen, Xin
Wang, He
Wang, Chaozhong
Guo, Yunjie
Lin, Yuxin
Huang, Yuhua
Hou, Jianquan
Wei, Xuedong
AGGREGATE, 2024, 5 (05):
[32] Aggregation-Induced Emission: Materials and Applications Volume 1 Introduction
Liu, Bin
Fujiki, Michiya
AGGREGATION-INDUCED EMISSION: MATERIALS AND APPLICATIONS, VOL 1, 2016, 1226 : 1 - 4
[33] Piperazine: a promising building block for aggregation-induced emission materials
Peng, Tuokai
Peng, Hui-Qing
JOURNAL OF MATERIALS CHEMISTRY C, 2023, 11 (38) : 12894 - 12899
[34] Efficient Aggregation-Induced Emission Manipulated by Polymer Host Materials
Wang, Xing-Huo
Song, Nan
Hou, Wei
Wang, Chun-Yu
Wang, Yan
Tang, Jun
Yang, Ying-Wei
ADVANCED MATERIALS, 2019, 31 (37)
[35] Perspective on Aggregation-induced Emission (AIE) Materials for Pathogen Detection
Zhou, Chengcheng
Zhu, Yaping
Guan, Weijiang
CURRENT ANALYTICAL CHEMISTRY, 2023, 19 (02) : 111 - 118
[36] Food Safety Detection Using Aggregation-induced Emission Materials
Lyu Y.-T.
Wang Q.
Zhu W.-H.
Faguang Xuebao/Chinese Journal of Luminescence, 2021, 42 (03): : 319 - 335
[37] Aggregation-Induced Emission: A Rising Star in Chemistry and Materials Science
Han, Ting
Yan, Dingyuan
Wu, Qian
Song, Nan
Zhang, Haoke
Wang, Dong
CHINESE JOURNAL OF CHEMISTRY, 2021, 39 (03) : 677 - 689
[38] Innovations in aggregation-induced emission materials for theranostics in the musculoskeletal system
Xu, Hanlin
Lin, Shangqian
Hua, Yinghui
BIOSENSORS & BIOELECTRONICS, 2025, 271
[39] Mesogens with aggregation-induced emission properties: Materials with a bright future
Voskuhl, Jens
Giese, Michael
AGGREGATE, 2022, 3 (01):
[40] Deciphering Design of Aggregation-Induced Emission Materials by Data Interpretation
Gong, Junyi
Deng, Ziwei
Xie, Huilin
Qiu, Zijie
Zhao, Zheng
Tang, Ben Zhong
ADVANCED SCIENCE, 2024,

← 1 2 3 4 5 →