Evidence for excision of ultraviolet-induced pyrimidine dimers from the DNA of human cells in vitro (Reprinted)

被引：0
|
作者：
Regan, JD [1 ]
Trosko, JE
Carrier, WL
机构：
[1] Oak Ridge Natl Lab, Div Biol, Oak Ridge, TN 37830 USA
[2] Michigan State Univ, Dept Nat Sci, E Lansing, MI 48823 USA
来源：
DNA REPAIR | 2004年 / 3卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Within 12-24 hr after human cells were irradiated with ultraviolet light, approximately 50% of the ultraviolet-induced pyrimidine dimers were lost from the DNA. Pyrimidine dimers were found in the TCA-soluble fraction of ultraviolet-irradiated cells at 24 hr. Excess thymidine, caffeine, or hydroxyurea. had no effect on the loss of pyrimidine dimers from the DNA of ultraviolet-irradiated cells.
引用
收藏
页码：92 / 98
页数：7
相关论文
共 50 条
  • [41] MECHANISM OF REPAIR OF DNA IN BACTERIOPHAGE .1. EXCISION OF PYRIMIDINE DIMERS FROM ULTRAVIOLET-IRRADIATED DNA BY AN EXTRACT OF T4-INFECTED CELLS
    SEKIGUCHI, M
    YASUDA, S
    OKUBO, S
    NAKAYAMA, H
    SHIMADA, K
    TAKAGI, Y
    JOURNAL OF MOLECULAR BIOLOGY, 1970, 47 (02) : 231 - +
  • [42] HARMAN INHIBITS THE REMOVAL OF PYRIMIDINE DIMERS FROM THE DNA OF HUMAN-CELLS
    CASTELLANI, A
    SETLOW, RB
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 98 (03) : 823 - 828
  • [43] Influence of cytosine methylation on ultraviolet-induced cyclobutane pyrimidine dimer formation in genomic DNA
    Rochette, Patrick J.
    Lacoste, Sandrine
    Therrien, Jean-Philippe
    Bastien, Nathalie
    Brash, Douglas E.
    Drouin, Regen
    MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2009, 665 (1-2) : 7 - 13
  • [44] A partial photoreactivation defect phenotype is not due to unrepaired ultraviolet-induced pyrimidine dimers in ultraviolet-sensitive mutants of Neurospora crassa
    Tsukada, Kotaro
    Yoshihara, Ryouhei
    Hatakeyama, Shin
    Ichiishi, Akihiko
    Tanaka, Shuuitsu
    GENES & GENETIC SYSTEMS, 2020, 95 (06) : 281 - 289
  • [45] DOSE-RESPONSE, WAVELENGTH DEPENDENCE AND RATE OF EXCISION OF ULTRAVIOLET RADIATION-INDUCED PYRIMIDINE DIMERS IN MOUSE SKIN DNA
    COOKE, A
    JOHNSON, BE
    BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 517 (01) : 24 - 30
  • [46] EXCISION OF PYRIMIDINE DIMERS FROM EPIDERMAL DNA AND NONSEMICONSERVATIVE EPIDERMAL DNA-SYNTHESIS FOLLOWING ULTRAVIOLET-IRRADIATION OF MOUSE SKIN
    BOWDEN, GT
    TROSKO, JE
    SHAPAS, BG
    BOUTWELL, RK
    CANCER RESEARCH, 1975, 35 (12) : 3599 - 3607
  • [47] Involvement of DNA replication in ultraviolet-induced apoptosis of mammalian cells
    Luis Francisco Zirnberger Batista
    Vanessa Chiganças
    Gabriela Brumatti
    Gustavo Pessini Amarante-Mendes
    Carlos Frederico Martins Menck
    Apoptosis, 2006, 11
  • [48] Involvement of DNA replication in ultraviolet-induced apoptosis of mammalian cells
    Batista, Luis Francisco Zirnberger
    Chigancas, Vanessa
    Brumatti, Gabriela
    Amarante-Mendes, Gustavo Pessini
    Martins Menck, Carlos Frederico
    APOPTOSIS, 2006, 11 (07) : 1139 - 1148
  • [49] IN-VITRO REPAIR OF OXIDATIVE AND ULTRAVIOLET-INDUCED DNA-DAMAGE IN SUPERCOILED NUCLEOID DNA BY HUMAN CELL EXTRACT
    COLLINS, AR
    FLEMING, IM
    GEDIK, CM
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1994, 1219 (03): : 724 - 727
  • [50] RESISTANCE OF MICROCOCCUS RADIODURANS TO ULTRAVIOLET RADIATION . 1 . ULTRAVIOLET-INDUCED LESIONS IN CELLS DNA
    SETLOW, JK
    DUGGAN, DE
    BIOCHIMICA ET BIOPHYSICA ACTA, 1964, 87 (04) : 664 - &
12345