Evidence for excision of ultraviolet-induced pyrimidine dimers from the DNA of human cells in vitro (Reprinted)

被引：0

作者：

Regan, JD ^{[1
]}

Trosko, JE

Carrier, WL

机构：

[1] Oak Ridge Natl Lab, Div Biol, Oak Ridge, TN 37830 USA

[2] Michigan State Univ, Dept Nat Sci, E Lansing, MI 48823 USA

来源：

DNA REPAIR | 2004年 / 3卷 / 01期

关键词：

D O I：

暂无

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Within 12-24 hr after human cells were irradiated with ultraviolet light, approximately 50% of the ultraviolet-induced pyrimidine dimers were lost from the DNA. Pyrimidine dimers were found in the TCA-soluble fraction of ultraviolet-irradiated cells at 24 hr. Excess thymidine, caffeine, or hydroxyurea. had no effect on the loss of pyrimidine dimers from the DNA of ultraviolet-irradiated cells.

引用

页码：92 / 98

页数：7

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