The flow synthesis of heterocycles for natural product and medicinal chemistry applications

被引：139
|
作者：
Baumann, Marcus [1 ]
Baxendale, Ian R. [1 ]
Ley, Steven V. [1 ]
机构：
[1] Univ Cambridge, Dept Chem, Innovat Technol Ctr Adv Chem Synth, Cambridge CB2 1EW, England
来源：
MOLECULAR DIVERSITY | 2011年 / 15卷 / 03期
关键词：
Flow synthesis; Micro-reactor; Meso-reactor; Solid-supported reagents; Heterocycles; Automated synthesis; MULTISTEP SYNTHESIS; THROUGH SYNTHESIS; ORGANIC-SYNTHESIS; REACTORS; BATCH; MICROREACTOR; FLUORINATION; SCAVENGERS; ALKYNES; STEP;
D O I：
10.1007/s11030-010-9282-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This article represents an overview of recent research from the Innovative Technology Centre in the field of flow chemistry which was presented at the FROST2 meeting in Budapest in October 2009. After a short introduction of this rapidly expanding field, we discuss some of our results with a main focus on the synthesis of heterocyclic compounds which we use in various natural product and medicinal chemistry programmes.
引用
收藏
页码：613 / 630
页数：18
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