机构:Northwestern Univ, Ctr Funct Genomics, Evanston, IL 60208 USA
Vitaterna, MH
Takahashi, JS
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机构:
Northwestern Univ, Ctr Funct Genomics, Evanston, IL 60208 USANorthwestern Univ, Ctr Funct Genomics, Evanston, IL 60208 USA
Takahashi, JS
[1
]
Turek, FW
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机构:Northwestern Univ, Ctr Funct Genomics, Evanston, IL 60208 USA
Turek, FW
机构:
[1] Northwestern Univ, Ctr Funct Genomics, Evanston, IL 60208 USA
[2] Northwestern Univ, Dept Neurobiol & Physiol, Evanston, IL 60208 USA
[3] Northwestern Univ, Howard Hughes Med Inst, Evanston, IL 60208 USA
[4] Northwestern Univ, Ctr Sleep & Circadian Biol, Evanston, IL USA
来源:
ALCOHOL RESEARCH & HEALTH
|
2001年
/
25卷
/
02期
关键词:
circadian rhythm;
time of day;
biological regulation;
biological adaptation;
temperature;
light;
hypothalamus;
neural cell;
gene expression;
mutagenesis;
sleep disorder;
physiological AODE (effects of alcohol or other drug use;
abuse;
and dependence);
D O I:
暂无
中图分类号:
R194 [卫生标准、卫生检查、医药管理];
学科分类号:
摘要:
The daily light-dark cycle governs rhythmic changes in the behavior and/or physiology of most species. Studies have found that these changes are governed by a biological clock, which in mammals is located in two brain areas called the suprachiasmatic nuclei. The circadian cycles established by this clock occur throughout nature and have a period of approximately 24 hours. In addition, these circadian cycles can be synchronized to external time signals but also can persist in the absence of such signals. Studies have found that the internal clock consists of an array of genes and the protein products they encode, which regulate various physiological processes throughout the body. Disruptions of the biological rhythms can impair the health and well-being of the organism.
机构:
Hosp Louis Mourier, AP HP, Colombes, France
Univ Paris, INSERM, UMRS 1149, Gastrointestinal & Metab Dysfunct Nutr Pathol, Paris, FranceHosp Louis Mourier, AP HP, Colombes, France
Duboc, Henri
Coffin, Benoit
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机构:
Hosp Louis Mourier, AP HP, Colombes, France
Univ Paris, INSERM, UMRS 1149, Gastrointestinal & Metab Dysfunct Nutr Pathol, Paris, FranceHosp Louis Mourier, AP HP, Colombes, France
Coffin, Benoit
Siproudhis, Laurent
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h-index: 0
机构:
CHU Rennes, Rennes, FranceHosp Louis Mourier, AP HP, Colombes, France