Fabrication of 3D Porous Micro-Channel for Artificial Capillary Blood Vessel Model

被引：0

作者：

Abu Bakar, Azrena ^{[1
]}

Nakajima, Masahiro ^{[2
]}

Yue, Tao ^{[1
]}

Hu, Chengzhi ^{[1
]}

Takeuchi, Masaru ^{[1
]}

Maruyama, Shoichi ^{[3
]}

Fukuda, Toshio ^{[4
,5
,6
]}

机构：

[1] Nagoya Univ, Dept Micronano Syst Engn, Nagoya, Aichi 4648601, Japan

[2] Nagoya Univ, Ctr Micronano Mechatron, Nagoya, Aichi 4648601, Japan

[3] Nagoya Univ, Dept Nephrol, Nagoya, Aichi 4648601, Japan

[4] Meijo Univ, Fac Sci & Engn, Nagoya, Aichi, Japan

[5] Nagoya Univ, Inst Adv Res, Nagoya, Aichi 4648601, Japan

[6] Beijing Inst Technol, Sch Mechatron Engn, Intelligent Robot Inst, Beijing 100081, Peoples R China

来源：

2013 PROCEEDINGS OF SICE ANNUAL CONFERENCE (SICE) | 2013年

关键词：

direct laser writing; porous micro-channel; glomerulus; UV lithography;

D O I：

暂无

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

We present the fabrication of 3D porous micro-channel for artificial capillary blood vessel model to study the pressure of glomerulus in vitro. The 3D porous micro-channel was fabricated by direct laser writing to mimic the complex structure of capillary blood vessel. It was designed to connect with micro-channels which were fabricated by UV lithography process. The 3D porous micro-channel was made of IP-L to represent the glomerulus structures via direct laser writing. The fabricated structure was observed by optical and electron microscope to reveal the fabrication errors due to shrinkage. Optimization of the direct laser writing method shows that IP-L is a better photoresist compare to Ormocomp for 3D porous micro-channel by solid model fabrication. The PDMS micro-channel has also been fabricated and assembled on the glass with the IP-L porous micro-channel. There was no leakage when fluid flow experiment was performed due to surface tension.

引用

页码：2661 / 2666

页数：6

共 50 条

[31] Fabrication of the porous hydroxyapatite implant by 3D printing
Qian, Chao
Sun, Jian
JOURNAL OF CERAMIC PROCESSING RESEARCH, 2013, 14 (04): : 513 - 516
[32] Fabrication of 3D Micro and Nanostructures for Photonic Applications
Cristea, D.
Obreja, P.
Dinescu, A.
Konstantinidis, G.
Rebigan, R.
Kusko, C.
PROCEEDINGS OF THE 7TH INTERNATIONAL CONFERENCE ON MULTI-MATERIAL MICRO MANUFACTURE (4M 2010), 2011, : 263 - 266
[33] Fabrication of monolithic 3D micro-systems
Preechaburana, Pakorn
Filippini, Daniel
LAB ON A CHIP, 2011, 11 (02) : 288 - 295
[34] Freeform fabrication of metals by 3D micro welding
Horii, T.
Yamamoto, Y.
Kirihara, S.
Miyamoto, Y.
Yamanaka, N.
VIRTUAL AND RAPID MANUFACTURING: ADVANCED RESEARCH IN VIRTUAL AND RAPID PROTOTYPING, 2008, : 509 - +
[35] 3D fabrication of artificial cell microenvironments for mechanobiology
Sonn, Annabelle
Tomba, Caterina
Selhuber-Unkel, Christine
Schamberger, Barbara
CURRENT OPINION IN BIOMEDICAL ENGINEERING, 2025, 33
[36] Micro- and nanostructural characteristics of 3D porous carriers ElastoPHB®-3D
Nemets, E. A.
Efimov, A. E.
Egorova, V. A.
Tonevitsky, A. G.
Sevastianov, V. I.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2008, 145 (03) : 371 - 373
[37] Micro-and nanostructural characteristics of 3D porous carriers ElastoPHB®-3D
E. A. Nemets
A. E. Efimov
V. A. Egorova
A. G. Tonevitsky
V. I. Sevastianov
Bulletin of Experimental Biology and Medicine, 2008, 145 : 371 - 373
[38] Non-Uniform Micro-Channel Design for Stacked 3D-ICs
Shi, Bing
Srivastava, Ankur
Wang, Peng
PROCEEDINGS OF THE 48TH ACM/EDAC/IEEE DESIGN AUTOMATION CONFERENCE (DAC), 2011, : 658 - 663
[39] 3D visualization of microvascular blood vessel networks
Computers & Graphics (Pergamon), 1995, 19 (01):
[40] 3D simulations of early blood vessel formation
Cavalli, F.
Gamba, A.
Naldi, G.
Semplice, M.
Valdembri, D.
Serini, G.
JOURNAL OF COMPUTATIONAL PHYSICS, 2007, 225 (02) : 2283 - 2300

← 1 2 3 4 5 →