Fabrication of 3D Porous Micro-Channel for Artificial Capillary Blood Vessel Model

被引：0

作者：

Abu Bakar, Azrena ^{[1
]}

Nakajima, Masahiro ^{[2
]}

Yue, Tao ^{[1
]}

Hu, Chengzhi ^{[1
]}

Takeuchi, Masaru ^{[1
]}

Maruyama, Shoichi ^{[3
]}

Fukuda, Toshio ^{[4
,5
,6
]}

机构：

[1] Nagoya Univ, Dept Micronano Syst Engn, Nagoya, Aichi 4648601, Japan

[2] Nagoya Univ, Ctr Micronano Mechatron, Nagoya, Aichi 4648601, Japan

[3] Nagoya Univ, Dept Nephrol, Nagoya, Aichi 4648601, Japan

[4] Meijo Univ, Fac Sci & Engn, Nagoya, Aichi, Japan

[5] Nagoya Univ, Inst Adv Res, Nagoya, Aichi 4648601, Japan

[6] Beijing Inst Technol, Sch Mechatron Engn, Intelligent Robot Inst, Beijing 100081, Peoples R China

来源：

2013 PROCEEDINGS OF SICE ANNUAL CONFERENCE (SICE) | 2013年

关键词：

direct laser writing; porous micro-channel; glomerulus; UV lithography;

D O I：

暂无

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

We present the fabrication of 3D porous micro-channel for artificial capillary blood vessel model to study the pressure of glomerulus in vitro. The 3D porous micro-channel was fabricated by direct laser writing to mimic the complex structure of capillary blood vessel. It was designed to connect with micro-channels which were fabricated by UV lithography process. The 3D porous micro-channel was made of IP-L to represent the glomerulus structures via direct laser writing. The fabricated structure was observed by optical and electron microscope to reveal the fabrication errors due to shrinkage. Optimization of the direct laser writing method shows that IP-L is a better photoresist compare to Ormocomp for 3D porous micro-channel by solid model fabrication. The PDMS micro-channel has also been fabricated and assembled on the glass with the IP-L porous micro-channel. There was no leakage when fluid flow experiment was performed due to surface tension.

引用

页码：2661 / 2666

页数：6

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