Statistical parameters in behavioral tasks and implications for sample size of C57BL/6J:129S6/SvEvTac mixed strain mice

被引：2
|
作者：
Estill, SJ
Fay, K
Garcia, JA
机构：
[1] Dept Internal Med, Mol Cardiol Div, Dallas, TX 75390 USA
[2] Univ Texas, SW Med Ctr, Dept Biochem, Dallas, TX 75390 USA
来源：
TRANSGENIC RESEARCH | 2001年 / 10卷 / 02期
关键词：
behavior; C57BL/6J; sample size; test battery; 129S6/SvEvTac;
D O I：
10.1023/A:1008955016170
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Most mixed strain progeny from gene-knockout experiments typically originate from C57BL/6J and one of the 129 substrains, frequently 129S6/SvEvTac. The results of this behavioral survey suggest that C57BL/6J:129S6/SvEvTac mixed strain mice are amenable to behavioral testing. The variability in behavioral tasks for subjects arising from this mixed strain genetic background does not preclude screening with a battery of behavioral tests. With clues provided by a screen of mixed strain subjects, follow-up analyses with isogenic, congenic, or F1 hybrid animals may be targeted to specific behavioral themes.
引用
收藏
页码：157 / 175
页数：19
相关论文
共 50 条
  • [1] Statistical Parameters in Behavioral Tasks and Implications for Sample Size of C57BL/6J:129S6/SvEvTac Mixed Strain Mice
    Sandi Jo Estill
    Kathleen Fay
    Joseph A. Garcia
    Transgenic Research, 2001, 10 : 157 - 175
  • [2] Behavioral and physiological mouse models for anxiety: effects of flesinoxan in 129S6/SvEvTac and C57BL/6J mice
    Bouwknecht, JA
    van der Gugten, J
    Groenink, L
    Olivier, B
    Paylor, RE
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2004, 494 (01) : 45 - 53
  • [3] A marker assisted selection protocol (MASP) to generate C57BL/6J or 129S6/SvEvTac speed congenic or consomic strains
    Estill, SJ
    Garcia, JA
    GENESIS, 2000, 28 (3-4) : 164 - 166
  • [4] Bile acid supplementation decreases body mass gain in C57BL/6J but not 129S6/SvEvTac mice without increasing energy expenditure
    Tobias Fromme
    Kristina Hüttinger
    Stefanie Maurer
    Yongguo Li
    Thomas Gantert
    Jarlei Fiamoncini
    Hannelore Daniel
    Sören Westphal
    Martin Klingenspor
    Scientific Reports, 9
  • [5] Bile acid supplementation decreases body mass gain in C57BL/6J but not 129S6/SvEvTac mice without increasing energy expenditure
    Fromme, Tobias
    Huettinger, Kristina
    Maurer, Stefanie
    Li, Yongguo
    Gantert, Thomas
    Fiamoncini, Jarlei
    Daniel, Hannelore
    Westphal, Soeren
    Klingenspor, Martin
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [6] Relationship between hemodynamics and atherosclerosis in aortic arches of apolipoprotein E-null mice on 129S6/SvEvTac and C57BL/6J genetic backgrounds
    Tomita, Hirofumi
    Hagaman, John
    Friedman, Morton H.
    Maeda, Nobuyo
    ATHEROSCLEROSIS, 2012, 220 (01) : 78 - 85
  • [7] Phenotypic characterization of C57BL/6J mice carrying the Disc1 gene from the 129S6/SvEv strain
    Juan, Liang-Wen
    Liao, Chun-Chieh
    Lai, Wen-Sung
    Chang, Chia-Yuan
    Pei, Ju-Chun
    Wong, Wan-Rong
    Liu, Chih-Min
    Hwu, Hai-Gwo
    Lee, Li-Jen
    BRAIN STRUCTURE & FUNCTION, 2014, 219 (04): : 1417 - 1431
  • [8] The mapping of quantitative trait loci underlying strain differences in locomotor activity between 129S6 and C57BL/6J mice
    Michele A. Kelly
    Malcolm J. Low
    Tamara J. Phillips
    Edward K. Wakeland
    Masashi Yanagisawa
    Mammalian Genome, 2003, 14 : 692 - 702
  • [9] Aortic Arch Curvature and Atherosclerosis Have Overlapping QTLs in Crosses Between 129S6/SvEvTac and C57BL/6J Apolipoprotein E-Null Mice
    Tomita, Hirofumi
    Zhilicheva, Svetlana
    Kim, Shinja
    Maeda, Nobuyo
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2010, 30 (11) : E205 - E205
  • [10] Phenotypic characterization of C57BL/6J mice carrying the Disc1 gene from the 129S6/SvEv strain
    Liang-Wen Juan
    Chun-Chieh Liao
    Wen-Sung Lai
    Chia-Yuan Chang
    Ju-Chun Pei
    Wan-Rong Wong
    Chih-Min Liu
    Hai-Gwo Hwu
    Li-Jen Lee
    Brain Structure and Function, 2014, 219 : 1417 - 1431
12345