Facile Preparation of Aryl Nitriles from Aryl Aldehydes in PEG-DME 250

被引:0
|
作者
Kang, Solbe [1 ]
Lee, Jong Chan [1 ]
机构
[1] Chung Ang Univ, Coll Sci, Dept Chem, Seoul 06974, South Korea
关键词
Aldehydes; aldoxime; nitriles; phosphorus; polyethylene; polyglyme; ONE-POT SYNTHESIS; HIGHLY EFFICIENT; IONIC LIQUID; CONVERSION; ALDOXIMES; CATALYST; AMIDES; MILD; DEHYDRATION; REAGENT;
D O I
10.2174/1570178618666210909103040
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile and efficient method is reported for the one-pot transformation of aryl aldehydes to aryl nitriles using hydroxylamine hydrochloride and phosphorus tribromide in PEGDME 250. The conversion of various aryl aldehydes to the corresponding aryl nitriles occurred smoothly in high yields under the present reaction conditions.
引用
收藏
页码:258 / 261
页数:4
相关论文
共 50 条
  • [21] Carbene reactivity from alkyl and aryl aldehydes
    Zhang, Lumin
    DeMuynck, Bethany M.
    Paneque, Alyson N.
    Rutherford, Joy E.
    Nagib, David A.
    SCIENCE, 2022, 377 (6606) : 649 - +
  • [22] A direct synthesis of 1-aryl- and 1-alkenylcyclopropylamines from aryl and alkenyl nitriles
    Bertus, P
    Szymoniak, J
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (18): : 7133 - 7136
  • [23] Copper-Catalyzed Synthesis of Aryl Thioamides from Aryl Aldehydes and Tetramethylthiuram Disulfide
    Zeng, Meng-Tian
    Wang, Min
    Peng, Han-Ying
    Cheng, Yu
    Dong, Zhi-Bing
    SYNTHESIS-STUTTGART, 2018, 50 (03): : 644 - 650
  • [24] Unusual Reactivity of Aryl Aldehydes with Triethyl Phosphite and Zinc Bromide: A Facile Preparation of Epoxides, Benzisoxazoles, and -Hydroxy Phosphonate Esters
    Raju, Potharaju
    Rajeshwaran, Ganesan Gobi
    Nandakumar, Meganathan
    Mohanakrishnan, Arasambattu K.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 2015 (16) : 3513 - 3523
  • [25] Facile synthesis of fluorinated 2-aryl-5,7 bisalkyl pyrazolo pyrimidines from arylalkyne nitriles
    Rao, V. V. V. N. S. Rama
    Lingaiah, B. P. B.
    Ezikiel, G.
    Yadla, R.
    Rao, P. Shanthan
    HETEROCYCLIC COMMUNICATIONS, 2006, 12 (3-4) : 275 - 280
  • [26] A facile synthesis of aryl isothiocyanates from arylamines
    Li, ZB
    Qian, XH
    Liu, Z
    Li, Z
    Song, GH
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2000, 32 (06) : 571 - 573
  • [27] Preparation and odor characteristics of nitriles derived from aldehydes
    Lan, Liyuan
    Huang, Shuai
    Liu, Yongguo
    Sun, Baoguo
    Tian, Hongyu
    FLAVOUR AND FRAGRANCE JOURNAL, 2020, 35 (04) : 425 - 434
  • [28] A CONVENIENT METHOD FOR THE PREPARATION OF NITRILES FROM ALDEHYDES AND ALDOXIMES
    YEH, MY
    TIEN, HJ
    TUNG, CH
    HWANG, CC
    WU, TS
    JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1988, 35 (06) : 459 - 462
  • [29] Aryl-substituted sulfonium betaines: Preparation and use in the epoxidation of aldehydes
    Forbes, David C.
    Amin, Sejal R.
    Bean, Christie J.
    Standen, Michael C.
    JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (21): : 8287 - 8290
  • [30] A FACILE PREPARATION OF 2-ARYLPROPIONALDEHYDE FROM 1-ARYL-1-PROPENE
    KIKUCHI, H
    KOGURE, K
    TOYODA, M
    CHEMISTRY LETTERS, 1984, (03) : 341 - 344